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  4. Recombinant Saccharomyces cerevisiae Mitochondrial division protein 1 (MDV1), partial

Recombinant Saccharomyces cerevisiae Mitochondrial division protein 1 (MDV1), partial

  • 中文名称：
    酿酒酵母MDV1重组蛋白
  • 货号：
    CSB-YP344026SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母MDV1重组蛋白
  • 货号：
    CSB-EP344026SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母MDV1重组蛋白
  • 货号：
    CSB-EP344026SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母MDV1重组蛋白
  • 货号：
    CSB-BP344026SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母MDV1重组蛋白
  • 货号：
    CSB-MP344026SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MDV1
  • Uniprot No.：
    P47025
  • 别名：
    MDV1; FIS2; GAG3; NET2; YJL112W; J0802; Mitochondrial division protein 1; Mitochondria fission 2 protein
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in mitochondrial fission. Has a partially redundant function to CAF4 in acting as an adapter protein, binding to FIS1 on the mitochondrial outer membrane and recruiting the dynamin-like GTPase DNM1 to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.
  • 基因功能参考文献：
    1. in addition to dimerization, the unusually long Mdv1 coiled coil serves a scaffolding function to stabilize the Mdv1-Fis1 complex. PMID: 22303011
    2. Although deletion of Ty3 spacer domain dramatically reduced retrotransposition, significant Gag3 processing and cDNA synthesis occurred. PMID: 21270167
    3. Mdv1 CC lies parallel to the bilayer with N termini at opposite ends bound to Fis1 and C-terminal beta-propeller domains (Dnm1-binding sites) extending into the cytoplasm PMID: 21149566
    4. the N terminus of Fis1 is a prerequisite to recruit Mdv1 to facilitate mitochondrial fission PMID: 15809300
    5. findings show that Dnm1p-dependent peroxisome fission requires Fis1p, Caf4p and Mdv1p; association of Caf4p and Mdv1p with peroxisomes relies on Fis1p PMID: 18445678

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  • 亚细胞定位：
    Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=Uniformly distributed on the cytoplasmic face of the mitochondrial outer membrane. This localization is dependent on FIS1. Reorganizes to punctate structures on mitochondria, corresponding to mitochondrial constriction sites, at a late step in mitochondrial division. This relocalization is dependent on DNM1.
  • 蛋白家族：
    WD repeat MDV1/CAF4 family
  • 数据库链接：

    KEGG: sce:YJL112W

    STRING: 4932.YJL112W

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