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  4. Recombinant Saccharomyces cerevisiae Metallothionein expression activator (ACE2), partial

Recombinant Saccharomyces cerevisiae Metallothionein expression activator (ACE2), partial

  • 中文名称：
    Recombinant Saccharomyces cerevisiae Metallothionein expression activator(ACE2) ,partial
  • 货号：
    CSB-YP325032SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Metallothionein expression activator(ACE2) ,partial
  • 货号：
    CSB-EP325032SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Metallothionein expression activator(ACE2) ,partial
  • 货号：
    CSB-EP325032SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Metallothionein expression activator(ACE2) ,partial
  • 货号：
    CSB-BP325032SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Metallothionein expression activator(ACE2) ,partial
  • 货号：
    CSB-MP325032SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ACE2
  • Uniprot No.：
    P21192
  • 别名：
    ACE2; YLR131C; L3123; L9606.10Metallothionein expression activator
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in regulating basal-level expression of CUP1. Activates EGT2 transcription in the absence of SWI5.
  • 基因功能参考文献：
    1. ACE2, a transcription factor required for septum destruction after cytokinesis, is a negative regulator of ethanol tolerance. PMID: 29789541
    2. Therefore, Ace2 and Swi5 are two negative regulators of ethanol yield during static fermentation of yeast cells, and both CTS1 and RPS4a are major effectors mediating these two transcription factors in regulating ethanol production. PMID: 26975390
    3. Data show that mutation of the Rts1 regulatory subunit of PP2A phosphatase (PP2ARts1 phosphatase) results in decreased HO endonuclease expression due to altered localization of the Ace2 transcription factor. PMID: 25352596
    4. Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae. PMID: 24145419
    5. show that Ace2 asymmetry is initiated in the elongated, but undivided, anaphase nucleus PMID: 22711697
    6. Data show that Ace2's nuclear localization is maintained by continuous Cbk1 activity and that inhibition of the kinase leads to immediate loss of phosphorylation and export to the cytoplasm. PMID: 20573982
    7. Regulation of CLN3 expression by Ace2 and Ash1 can account for the differential regulation of Start in response to cell size in mothers and daughters. PMID: 19841732
    8. Phosphorylation of the C-terminal site of Cbk1 is regulated over the cell cycle and requires Ace2 as well as all RAM network components.Ace2 is not only a downstream target of Cbk1 but also reinforces activation of its upstream regulator. PMID: 17145962
    9. In the daughter cell nucleus Cbk1p phosphorylates the Ace2p nuclear export signal, and the phosphorylation blocks the export of Ace2p via Crm1p. PMID: 18076379
    10. the precise timing of Ace2 accumulation in the nucleus involves both a nuclear export sequence and a nuclear localization signal, whose activities are regulated by phosphorylation PMID: 18292088

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: sce:YLR131C

    STRING: 4932.YLR131C

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