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  4. Recombinant Rat Unconventional myosin-Id (Myo1d), partial

Recombinant Rat Unconventional myosin-Id (Myo1d), partial

  • 中文名称：
    大鼠Myo1d重组蛋白
  • 货号：
    CSB-YP733927RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Myo1d重组蛋白
  • 货号：
    CSB-EP733927RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Myo1d重组蛋白
  • 货号：
    CSB-EP733927RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Myo1d重组蛋白
  • 货号：
    CSB-BP733927RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Myo1d重组蛋白
  • 货号：
    CSB-MP733927RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Myo1d
  • Uniprot No.：
    Q63357
  • 别名：
    Myo1d; Myr4; Unconventional myosin-Id; Myosin heavy chain myr 4
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Unconventional myosin that functions as actin-based motor protein with ATPase activity. Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells.
  • 基因功能参考文献：
    1. This study demonistrated that myosin ID is expressed in myelinating oligodendrocytes in rat nerve system. PMID: 24903835
    2. In conclusion, for the surface loops of Myo1c explored to date, the parent myosin dominates the behavior and loop 1 modulates the properties of the parent myosin. The loops themselves do not confer predictable properties on the parent myosin. PMID: 20039646
    3. At apical surfaces of supporting cells surrounding hair cells in auditory epithelia of postnatal rats. In vestibular epithelia, in a ring within apical pole of hair cell. Prominent only immediately after birth. PMID: 12486594
    4. Results support a model in which Myo1c possesses a strain-sensing ADP-release mechanism, which allows it to adapt to mechanical load. PMID: 15014434
    5. Myr4 mRNA was abundant in spinal cord motor neurons PMID: 15809075
    6. Results describe Myo1d ATPase activity as a function of its IQ-motifs and calcium-calmodulin binding. PMID: 15853803

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  • 亚细胞定位：
    Cytoplasm. Perikaryon. Cell projection, dendrite. Early endosome. Cytoplasm, cell cortex.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 组织特异性：
    Detected on tracheal epithelial cells, and on epithelial cells and brush border cells in duodenum, jejunum and ileum. Detected on myelinated white matter in the cerebellum, and the myelinated part of the optic nerve. Detected on mature oligodendrocites. D
  • 数据库链接：

    KEGG: rno:25485

    STRING: 10116.ENSRNOP00000004609

    UniGene: Rn.10376

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