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  4. Recombinant Rat Retinol-binding protein 1 (Rbp1)

Recombinant Rat Retinol-binding protein 1 (Rbp1)

  • 中文名称：
    大鼠Rbp1重组蛋白
  • 货号：
    CSB-YP019480RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Rbp1重组蛋白
  • 货号：
    CSB-EP019480RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Rbp1重组蛋白
  • 货号：
    CSB-EP019480RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Rbp1重组蛋白
  • 货号：
    CSB-BP019480RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Rbp1重组蛋白
  • 货号：
    CSB-MP019480RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Rbp1
  • Uniprot No.：
    P02696
  • 别名：
    Rbp1; Rbp-1; Retinol-binding protein 1; Cellular retinol-binding protein; CRBP; Cellular retinol-binding protein I; CRBP-I
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-135
  • 氨基酸序列
    PVDFNGYWK MLSNENFEEY LRALDVNVAL RKIANLLKPD KEIVQDGDHM IIRTLSTFRN YIMDFQVGKE FEEDLTGIDD RKCMTTVSWD GDKLQCVQKG EKEGRGWTQW IEGDELHLEM RAEGVTCKQV FKKVH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cytoplasmic retinol-binding protein. Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis.
  • 基因功能参考文献：
    1. CRBP1 contributes to pulmonary structural remodeling after myocardial infarction. PMID: 22944241
    2. a potential role of CRBP1 in the regulation of beta-catenin turnover which can greatly affect the process of osteogenesis and adipogenesis of mesenchymal stem cells PMID: 22230368
    3. Structure and backbone dynamics of Apo- and holo-cellular retinol-binding protein in solution PMID: 11934897
    4. CRBP1 has a role in vitamin A metabolism and its absence may play a role in ovarian cancer oncogenesis PMID: 12631600
    5. analysis of conformational flexibility of rat cellular retinol-binding protein I (CRBP I) and cellular retinol-binding protein II (CRBP II) PMID: 12850148
    6. differences in conformational flexibility between the ligand-free and ligand-bound forms of cellular retinol-binding protein type I PMID: 16755609
    7. As the convoluted proximal tubular epithelial cells dedifferentiate during fibrosis, CRBP-I expression decreases in adriamycin-induced fibrotic rat kidney. PMID: 18503097

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  • 亚细胞定位：
    Cytoplasm. Lipid droplet.
  • 蛋白家族：
    Calycin superfamily, Fatty-acid binding protein (FABP) family
  • 数据库链接：

    KEGG: rno:25056

    STRING: 10116.ENSRNOP00000018622

    UniGene: Rn.902

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