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  4. Recombinant Rat Prolyl 3-hydroxylase 1 (Lepre1)

Recombinant Rat Prolyl 3-hydroxylase 1 (Lepre1)

  • 中文名称：
    大鼠P3h1重组蛋白
  • 货号：
    CSB-YP870819RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠P3h1重组蛋白
  • 货号：
    CSB-EP870819RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠P3h1重组蛋白
  • 货号：
    CSB-EP870819RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠P3h1重组蛋白
  • 货号：
    CSB-BP870819RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠P3h1重组蛋白
  • 货号：
    CSB-MP870819RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    P3h1
  • Uniprot No.：
    Q9R1J8
  • 别名：
    P3h1; Lepre1; Prolyl 3-hydroxylase 1; EC 1.14.11.7; Leucine- and proline-enriched proteoglycan 1; Leprecan-1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    15-728
  • 氨基酸序列
    ESEPEW NVAAPDLLYA EGTAAYARGD WPGVVLNMER ALRSRAALRA LRLRCRTRCA TELPWAPDLD LGPASSLNHD PGAAALHDLR FFGALLRRAA CLRRCLGPPS AHLLSEELDL EFNKRSPYNY LQVAYFKINK LEKAVAAAHT FFVGNPEHME MRQNLDYYQT MSGVKEEDFK DLEAKPHMHE FRLGVRLYSE EKPLEAVPHL EAALQEYFVA DEECRALCEG PYDYDGYNYL DYSADLFQAI TDHYVQVLSC KQNCVTELAS HPSREKPFED FLPSHYNYLQ FAYYNIGNYT QAIECAKTYL LFFPNDEVMS QNLAYYTAVL GEEEASSISP RENAQEYRHR SLLEKELLFF AYDIFGIPFV DPDSWTPEEV IPKRLQEKQK SERETAVRIS QEIGNLMKEI ETLVEEKTKE SLDVSRLTRE GGPLLYEGIN LTMNSKVLNG SQRVVMDGVI SDDECQELQR LTNAAATSGD GYRGQTSPHT PNEKFYGVTV LKALKLGQEG KVPLQSAHMY YNVTEKVRRV MESYFRLDTP LYFSYSHLVC RTAIEESQAE RKDSSHPVHV DNCILNAESL VCIKEPPAYT FRDYSAILYL NGDFDGGNFY FTELDAKTVT AEVQPQCGRA VGFSSGTENP HGVKAVTRGQ RCAIALWFTL DPRHSERDRV QADDLVKMLF SPEEVDLPQE QPLPDQQGSP KPGEESLSDR ESQPKDEL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
  • 基因功能参考文献：
    1. Regulated expression of leprecan during glomerular development or hypertrophy coupled with its reported prolyl hydroxylase activity plays a role during basement membrane assembly. PMID: 17495866
  • 亚细胞定位：
    Endoplasmic reticulum. Secreted, extracellular space, extracellular matrix. Note=Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG).
  • 蛋白家族：
    Leprecan family
  • 组织特异性：
    Expressed in basement membranes of cardiac muscle, skeletal muscle, central nervous system, intestinal tract, trachea, ear, skin, liver and kidney. In kidney, localizes to the glomerular basement membrane, mesangial matrix and Bowman's capsule of the neph
  • 数据库链接：

    KEGG: rno:114200

    STRING: 10116.ENSRNOP00000010395

    UniGene: Rn.13741

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