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  4. Recombinant Rat Potassium channel subfamily T member 2 (Kcnt2), partial

Recombinant Rat Potassium channel subfamily T member 2 (Kcnt2), partial

  • 中文名称：
    大鼠Kcnt2重组蛋白
  • 货号：
    CSB-YP757786RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Kcnt2重组蛋白
  • 货号：
    CSB-EP757786RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Kcnt2重组蛋白
  • 货号：
    CSB-EP757786RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Kcnt2重组蛋白
  • 货号：
    CSB-BP757786RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Kcnt2重组蛋白
  • 货号：
    CSB-MP757786RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Kcnt2
  • Uniprot No.：
    Q6UVM4
  • 别名：
    Kcnt2; SlickPotassium channel subfamily T member 2; Sequence like an intermediate conductance potassium channel subunit; Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1.
  • 基因功能参考文献：
    1. Our data show SLICK expression is predominantly under the control of NFkappaB. Because neuronal NFkappaB activation occurs during stressful stimuli such as hypoxia and injury, our findings suggest that SLICK is a neuroprotective gene. PMID: 26100633
    2. Cloning and regulation of slick channel activity. PMID: 14684870
    3. we report the localization of Slick in the rat central nervous system using in situ and immunohistochemical techniques PMID: 15717307
    4. Heteromer formation between Slick and Slack-B requires a specific epitope that is found in the N-terminal domain of Slack-B and that is absent in the Slack-A isoform. PMID: 19403831
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamily
  • 组织特异性：
    Detected in brain, and at low levels in heart. Detected in brainstem, including auditory neurons such as the medial nucleus of the trapezoid body. Detected in the olfactory bulb, red nucleus, facial nucleus, pontine nucleus, oculomotor nucleus, substantia
  • 数据库链接：

    KEGG: rno:304827

    UniGene: Rn.212417

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