Recombinant Rat Neurogenic locus notch homolog protein 2 (Notch2), partial

中文名称：

大鼠Notch2重组蛋白
货号：

CSB-YP882539RA
规格：
来源：

Yeast
其他：

中文名称：

大鼠Notch2重组蛋白
货号：

CSB-EP882539RA
规格：
来源：

E.coli
其他：

中文名称：

大鼠Notch2重组蛋白
货号：

CSB-EP882539RA-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

大鼠Notch2重组蛋白
货号：

CSB-BP882539RA
规格：
来源：

Baculovirus
其他：

中文名称：

大鼠Notch2重组蛋白
货号：

CSB-MP882539RA
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

Notch2
Uniprot No.：

Q9QW30
别名：

Notch2Neurogenic locus notch homolog protein 2; Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]
种属：

Rattus norvegicus (Rat)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells.
亚细胞定位：

[Notch 2 extracellular truncation]: Cell membrane; Single-pass type I membrane protein.; [Notch 2 intracellular domain]: Nucleus. Cytoplasm.
蛋白家族：

NOTCH family
组织特异性：

Highly expressed in the spleen and choroid plexus in the brain. Expressed in postnatal central nervous system (CNS) germinal zones and, in early postnatal life, within numerous cells throughout the CNS. It is more highly localized to ventricular germinal
数据库链接：

STRING: 10116.ENSRNOP00000025718

UniGene: Rn.65930

Recombinant Rat Neurogenic locus notch homolog protein 2 (Notch2), partial

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