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  4. Recombinant Rat Microtubule-associated protein 1A (Map1a), partial

Recombinant Rat Microtubule-associated protein 1A (Map1a), partial

  • 中文名称：
    大鼠Map1a重组蛋白
  • 货号：
    CSB-YP013400RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Map1a重组蛋白
  • 货号：
    CSB-EP013400RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Map1a重组蛋白
  • 货号：
    CSB-EP013400RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Map1a重组蛋白
  • 货号：
    CSB-BP013400RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Map1a重组蛋白
  • 货号：
    CSB-MP013400RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Map1a
  • Uniprot No.：
    P34926
  • 别名：
    Map1a; Mtap1aMicrotubule-associated protein 1A; MAP-1A) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2]
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements.
  • 基因功能参考文献：
    1. Disruption of MAP1A could be a very early manifestation of amyloid-beta-mediated synaptic dysfunction--one that presages the clinical onset of Alzheimer's disease by years. PMID: 22252785
    2. Data show that microtubule associated protein 1A gene expression is upregulated by exposure to conditions of increased gravity. PMID: 12480186
    3. After brain ischemia, MAP1A immunoreactivity was significantly decreased in the cerebral cortex and the hippocampus. PMID: 12757367
    4. there is a novel interaction between the C-terminal tail of the BKCa channel and the light chain of MAP1A, which enables channel association with and modulation by the cytoskeleton PMID: 15251455
    5. MAP1A expression is required for activity-dependent growth, branching, and stabilization of the dendritic arbor. PMID: 16243028
    6. The consensus GK-binding sequence in MAP1a and demonstrate that PSD-95 can use a similar interaction mode to bind diverse protein partners is determined. PMID: 17220895
    7. Microtubule-associated protein-1 light chain-3 (LC3) protein and mRNA levels were significantly increased exclusively in denervated muscles from chloroquine-treated rats. PMID: 17643062
    8. Presynaptic surface localization of Ca(v)2.2 is mediated through its interaction with light chain 2 (LC2) of microtubule-associated protein MAP1A. PMID: 18971475

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    MAP1 family
  • 组织特异性：
    Brain, heart and muscle.
  • 数据库链接：

    KEGG: rno:25152

    STRING: 10116.ENSRNOP00000019320

    UniGene: Rn.11402

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