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  4. Recombinant Rat Gamma-butyrobetaine dioxygenase (Bbox1)

Recombinant Rat Gamma-butyrobetaine dioxygenase (Bbox1)

  • 中文名称：
    Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
  • 货号：
    CSB-YP870793RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
  • 货号：
    CSB-EP870793RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
  • 货号：
    CSB-EP870793RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
  • 货号：
    CSB-BP870793RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
  • 货号：
    CSB-MP870793RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Bbox1
  • Uniprot No.：
    Q9QZU7
  • 别名：
    Bbox1; Bbh; Gamma-butyrobetaine dioxygenase; EC 1.14.11.1; Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-387
  • 氨基酸序列
    MHCAILKAEA VDGARLMQIF WHDGAESLYP AVWLRDNCQC SDCYLHSAKA RKLLLEALDV NIRMDDLTFD QKKVYITWPN GHYSEFEANW LKKRCFSQEA RAGLQGELFL PECQYWGSEL QLPTLNFEDV LNDDDHAYKW LSSLKKVGIV RLTGAADKRG EIIKLGKRIG FLYLTFYGHT WQVQDKIDAN NVAYTTGKLS FHTDYPALHH PPGVQLLHCI KQTVTGGDSE IVDGFNVCQK LKEKNPQAFS ILSSTFVDFT DIGVDYCDFS VQSKHKIIEL DDKGQVVRIN FNNATRDTVF DVPIERVQPF YAALKEFVDL MNSKEYKYTF KMNPGDVITF DNWRLLHGRR SYEAGTEISR HLEGAYADWD VVMSRLRILR QRVMNGN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
  • 基因功能参考文献：
    1. Data suggest that expression of BBH mRNA and protein is up-regulated in liver with training in physical activity; in kidney, only BBH mRNA expression is up-regulated. PMID: 22014179
    2. Thyroid hormone controls carnitine status through modifications of gamma-butyrobetaine hydroxylase activity and gene expression PMID: 11964131
    3. Alterations in enzyme activities in the pivalate-treated rats are not regulated at the transcriptional level, and are apparently related to post-transcriptional effects on the enzymes themselves. PMID: 15795431
    4. BBH mRNA, however, was detected during the suckling period onwards and its abundance was not changed significantly by maturation PMID: 19150623
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Gamma-BBH/TMLD family
  • 组织特异性：
    Expressed in the liver and in some extend in the testis and the epididymis.
  • 数据库链接：

    KEGG: rno:64564

    STRING: 10116.ENSRNOP00000006197

    UniGene: Rn.16333

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