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  4. Recombinant Rat Contactin-associated protein 1 (Cntnap1), partial

Recombinant Rat Contactin-associated protein 1 (Cntnap1), partial

  • 中文名称：
    Recombinant Rat Contactin-associated protein 1(Cntnap1) ,partial
  • 货号：
    CSB-YP005692RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-associated protein 1(Cntnap1) ,partial
  • 货号：
    CSB-EP005692RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-associated protein 1(Cntnap1) ,partial
  • 货号：
    CSB-EP005692RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-associated protein 1(Cntnap1) ,partial
  • 货号：
    CSB-BP005692RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-associated protein 1(Cntnap1) ,partial
  • 货号：
    CSB-MP005692RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cntnap1
  • Uniprot No.：
    P97846
  • 别名：
    Cntnap1; Caspr; Nrxn4Contactin-associated protein 1; Caspr; Caspr1; Neurexin IV; Neurexin-4; Paranodin; p190
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
  • 基因功能参考文献：
    1. E. coli exploits Caspr1 as a host receptor for penetration of the blood-brain barrier, resulting in meningitis PMID: 29895952
    2. Caspr labeling was observed through much of the retina, including horizontal, bipolar, amacrine, and ganglion cells. PMID: 21031018
    3. The fact that caspr follows the movement of the spiraling membrane has a direct affect on the interpretation of the way in which myelin is formed. PMID: 19170162
    4. Neurofascin is a glial receptor for the paranodin/Caspr-contactin axonal complex at the axoglial junction. PMID: 11839274
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein. Cell junction, paranodal septate junction.
  • 蛋白家族：
    Neurexin family
  • 组织特异性：
    Predominantly expressed in brain. In myelinated nerve fibers of the CNS predominantly found in paranodal axoglial junctions. In unmyelinated nerve fibers of the CNS diffusely distributed along the entire surface. Weak expression is detected in ovary, panc
  • 数据库链接：

    KEGG: rno:84008

    STRING: 10116.ENSRNOP00000027505

    UniGene: Rn.88654

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