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  4. Recombinant Rat Contactin-2 (Cntn2), partial

Recombinant Rat Contactin-2 (Cntn2), partial

  • 中文名称：
    Recombinant Rat Contactin-2(Cntn2) ,partial
  • 货号：
    CSB-YP005687RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-2(Cntn2) ,partial
  • 货号：
    CSB-EP005687RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-2(Cntn2) ,partial
  • 货号：
    CSB-EP005687RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-2(Cntn2) ,partial
  • 货号：
    CSB-BP005687RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Contactin-2(Cntn2) ,partial
  • 货号：
    CSB-MP005687RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cntn2
  • Uniprot No.：
    P22063
  • 别名：
    Cntn2; Tax1Contactin-2; Axonal glycoprotein TAG-1; Axonin-1; Transient axonal glycoprotein 1; TAX-1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in the initial growth and guidance of axons. May be involved in cell adhesion. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region.
  • 基因功能参考文献：
    1. RT-PCR and Western blotting methods showed that 20 muM Abeta25-35 could increase the expression levels of TAG1, APP, AICD and p53 (P<0.01) while they decreased in BMSCs + Abeta25-35 group PMID: 26722394
    2. Expressed by Schwann cells and oligodendrocytes and is localized to the juxtaparanodal region of myelinated fibers. PMID: 11943804
    3. Tag-1 is expressed in migrating embryonic neurons that will form the lateral reticular and basilar pontine nuclei. PMID: 12182881
    4. Adoptive transfer of TAG-1-specific T cells induced encephalitis characterized by a preferential inflammation of gray matter of the spinal cord and cortex, identifying TAG-1 as an autoantigen targeted by T cells PMID: 19416878
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.
  • 蛋白家族：
    Immunoglobulin superfamily, Contactin family
  • 组织特异性：
    In neural tissues in embryos, and in adult brain, spinal cord and cerebellum.
  • 数据库链接：

    KEGG: rno:25356

    STRING: 10116.ENSRNOP00000012190

    UniGene: Rn.89910

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