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  4. Recombinant Rat Ankyrin repeat and SAM domain-containing protein 6 (Anks6), partial

Recombinant Rat Ankyrin repeat and SAM domain-containing protein 6 (Anks6), partial

  • 中文名称：
    Recombinant Rat Ankyrin repeat and SAM domain-containing protein 6(Anks6) ,partial
  • 货号：
    CSB-YP001808RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Ankyrin repeat and SAM domain-containing protein 6(Anks6) ,partial
  • 货号：
    CSB-EP001808RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Ankyrin repeat and SAM domain-containing protein 6(Anks6) ,partial
  • 货号：
    CSB-EP001808RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Ankyrin repeat and SAM domain-containing protein 6(Anks6) ,partial
  • 货号：
    CSB-BP001808RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Ankyrin repeat and SAM domain-containing protein 6(Anks6) ,partial
  • 货号：
    CSB-MP001808RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Anks6
  • Uniprot No.：
    P0C0T2
  • 别名：
    Anks6; Pkdr1; Samd6Ankyrin repeat and SAM domain-containing protein 6; Polycystic kidney disease protein 1; SamCystin; Sterile alpha motif domain-containing protein 6; SAM domain-containing protein 6
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for renal function.
  • 基因功能参考文献：
    1. In vivo evidence for a causal link between the novel Anks6((p.R823W)) gene mutation and polycystic kidney disease. PMID: 21119215
    2. aberrant expression and mislocalization of R823W SamCystin lead to increased cell proliferation and renal cyst formation PMID: 20719982
    3. Susceptibility to renal cyst formation in the (cy/+) rat is caused by a missense mutation in Pkdr1 encoding the novel protein SamCystin. PMID: 18434273
    4. Bicc1 and SamCystin interact at the protein level suggesting that they function in a common molecular pathway that when perturbed, is involved in cystogenesis. PMID: 19324013
  • 相关疾病：
    Defects in Anks6 are the cause of polycystic kidney disease (cy). Heterozygous cy rats are characterized by progressive formation and enlargement of cysts in kidneys.
  • 亚细胞定位：
    Cell projection, cilium. Cytoplasm.
  • 组织特异性：
    Widely expressed with moderate level in brain, skeletal muscle and testis. Expressed in renal tubules.
  • 数据库链接：

    KEGG: rno:362515

    STRING: 10116.ENSRNOP00000056754

    UniGene: Rn.101322

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