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  4. Recombinant Rat Activity-dependent neuroprotector homeobox protein (Adnp), partial

Recombinant Rat Activity-dependent neuroprotector homeobox protein (Adnp), partial

  • 中文名称：
    Recombinant Rat Activity-dependent neuroprotector homeobox protein(Adnp) ,partial
  • 货号：
    CSB-YP881335RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Activity-dependent neuroprotector homeobox protein(Adnp) ,partial
  • 货号：
    CSB-EP881335RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Activity-dependent neuroprotector homeobox protein(Adnp) ,partial
  • 货号：
    CSB-EP881335RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Activity-dependent neuroprotector homeobox protein(Adnp) ,partial
  • 货号：
    CSB-BP881335RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Activity-dependent neuroprotector homeobox protein(Adnp) ,partial
  • 货号：
    CSB-MP881335RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Adnp
  • Uniprot No.：
    Q9JKL8
  • 别名：
    Adnp; Activity-dependent neuroprotector homeobox protein; Activity-dependent neuroprotective protein
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
  • 基因功能参考文献：
    1. These findings demonstrate that the down-regulation of protein ADNP is an early pathological alteration and may contribute to dopaminergic neurodegeneration in Parkinson's disease PMID: 27003787
    2. the newly identified shared microtubule target of NAP/ADNP is directly implicated in synaptic plasticity, explaining the breadth and efficiency of neuroprotective/neurotrophic capacities PMID: 25178163
    3. NAP is an ADNP derived peptide that modulates the tubulin pool in mice and rats PMID: 23272107
    4. An endogenous PACAP-mediated ADNP signaling system increases malignant peripheral nerve sheath tumor cell resistance to hydrogen-peroxide-induced death upon serum starvation. PMID: 22454142
    5. Results suggest that nitric oxide regulates activity-dependent neuroprotective protein in the dentate gyrus under both basal and pathophysiological conditions. PMID: 19130308
    6. NAPVSIPQ peptide component was shown to inhibit Abeta aggregation; part of the neuroprotective mechanism is through modulation of toxic protein folding in the extracellular milieu PMID: 14706557
    7. These observations suggest a complex interaction of NO-NGF with PPTA/SP and ADNP-VIP in neuron-glial communication when neurons are stressed. PMID: 17952636
    8. Widespread expression of ADNP may correlate with wide-ranging protective effects, and the cytoplasmic and axonal localisation of ADNP-like immunoreactivity suggests additional, non-transcriptional functions of ADNP. PMID: 18072088
    9. These findings identify a mechanism for ADNP regulation of glial-neuronal interactions in developing cerebellum and a pathogenesis of ethanol neurotoxicity. PMID: 19047645

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: rno:64622

    STRING: 10116.ENSRNOP00000014595

    UniGene: Rn.48777

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