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  4. Recombinant Pseudomonas aeruginosa Biofilm dispersion protein BdlA (bdlA)

Recombinant Pseudomonas aeruginosa Biofilm dispersion protein BdlA (bdlA)

  • 中文名称：
    Recombinant Pseudomonas aeruginosa Biofilm dispersion protein BdlA(bdlA)
  • 货号：
    CSB-YP872741EZX
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Pseudomonas aeruginosa Biofilm dispersion protein BdlA(bdlA)
  • 货号：
    CSB-EP872741EZX
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Pseudomonas aeruginosa Biofilm dispersion protein BdlA(bdlA)
  • 货号：
    CSB-EP872741EZX-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Pseudomonas aeruginosa Biofilm dispersion protein BdlA(bdlA)
  • 货号：
    CSB-BP872741EZX
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Pseudomonas aeruginosa Biofilm dispersion protein BdlA(bdlA)
  • 货号：
    CSB-MP872741EZX
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    bdlA
  • Uniprot No.：
    Q9I3S1
  • 别名：
    bdlA; PA1423; Biofilm dispersion protein BdlA; Chemotaxis regulator BdlA
  • 种属：
    Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-417
  • 氨基酸序列
    MAALDRSMAR VEFDPDGNIT DANENFLTLL GYRRDEILGK PHRQLCDGAY AQSEDYRRFW ERLRRGEHFS GRCKRITREG RPLWLEATYN PVRDGQGRLL KVVKYASDID AIVHQEHEMQ SKLDALSRSM AMIEFDLDGN VLAANDNFLA TMGYGRAELA SANHRQFCEP GYRDGPQYAD LWRRLNRGEY VTGQFRRVHR NGQPVWLEAS YNPVYDADGK LYKVVKFASD VSDRMRRYQA EADNAHQAHT LSTETRTVAE HGALIIQSAV EEMLKIANTL DASSLNIGEL SQHSQQITSI VNTIREIAEQ TNLLALNAAI EAARAGDQGR GFAVVADEVR QLAERTSKST KEIADMIGRI QTGTRSVIDD MQHSQEQARR GVELANEAGA AILGIRESTH KVVEAVQQFS RTLNADL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface.
  • 基因功能参考文献：
    1. Data suggest that expression of genes contributing to virulence of Pseudomonas aeruginosa is nearly 30-fold reduced in biofilm cells relative to planktonic cells; expression of BdlA and phosphodiesterase DipA appears to follow the opposite pattern. PMID: 24901523
    2. Data indicate that the mechanism of BdlA function may have implications for the control of biofilm-related infections. PMID: 23012421
    3. The findings suggest that BdlA plays a role in intracellular sensing of dispersion-inducing conditions and together with DipA forms a regulatory network that modulates an intracellular cyclic d-GMP (c-di-GMP) pool to enable dispersion. PMID: 22923587
    4. Our findings suggest that BdlA may be a link between sensing environmental cues, c-di-GMP levels, and detachment PMID: 17050921
  • 数据库链接：

    KEGG: pae:PA1423

    STRING: 208964.PA1423

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