Recombinant Pig Myocardin (MYOCD), partial

中文名称：

野猪MYOCD重组蛋白
货号：

CSB-YP015357PI
规格：
来源：

Yeast
其他：

中文名称：

野猪MYOCD重组蛋白
货号：

CSB-EP015357PI
规格：
来源：

E.coli
其他：

中文名称：

野猪MYOCD重组蛋白
货号：

CSB-EP015357PI-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

野猪MYOCD重组蛋白
货号：

CSB-BP015357PI
规格：
来源：

Baculovirus
其他：

中文名称：

野猪MYOCD重组蛋白
货号：

CSB-MP015357PI
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

MYOCD
Uniprot No.：

Q7YR76
别名：

MYOCD; Myocardin
种属：

Sus scrofa (Pig)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis, urinary bladder development, and differentiation of the smooth muscle cell lineage (myogenesis).
基因功能参考文献：
1. a moderate inhibition (e.g., normalization) of the activated MYOCD signaling in the diseased heart may be promising from a therapeutic point of view PMID: 22028870
2. MYOCD DeltaExon 11 may participate in modulating smooth muscle cell phenotype, potentially acting as a dominant-negative repressor of contraction-related genes. PMID: 21792927
3. Data show that forced myocd-A expression in the LVFW caused abnormal ECG. PMID: 19247948
4. Thrombin stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin. PMID: 19574550
亚细胞定位：

Nucleus.
组织特异性：

Expressed in the heart and in smooth muscle cells-containing tissues (aorta, pulmonary vein, lung), but is not detectable in skeletal muscle, liver, kidney and spleen.
数据库链接：

KEGG: ssc:396571

UniGene: Ssc.18555

Recombinant Pig Myocardin (MYOCD), partial

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