Recombinant Pig Dual oxidase 2 (DUOX2), partial

中文名称：

野猪DUOX2重组蛋白
货号：

CSB-YP007229PI
规格：
来源：

Yeast
其他：

中文名称：

野猪DUOX2重组蛋白
货号：

CSB-EP007229PI
规格：
来源：

E.coli
其他：

中文名称：

野猪DUOX2重组蛋白
货号：

CSB-EP007229PI-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

野猪DUOX2重组蛋白
货号：

CSB-BP007229PI
规格：
来源：

Baculovirus
其他：

中文名称：

野猪DUOX2重组蛋白
货号：

CSB-MP007229PI
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

DUOX2
Uniprot No.：

Q8HZK2
别名：

DUOX2Dual oxidase 2; EC 1.11.1.-; EC 1.6.3.1; NADH/NADPH thyroid oxidase p138-tox
种属：

Sus scrofa (Pig)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
基因功能参考文献：
1. A novel recessive c.1226A>G transition of the dual oxidase 2 gene was identified as the causative mutation for a severe congenital hypothyroidism model together with anemia and T lymphopenia which mimics the clinical features of hypothyroid patients PMID: 28972010
2. the dual oxidase 2 N-terminal region is targeted to the plasma membrane PMID: 15150274
3. Expression along the length of the gastrointestinal tract. PMID: 15591162
亚细胞定位：

Apical cell membrane; Multi-pass membrane protein. Cell junction.
蛋白家族：

Peroxidase family
组织特异性：

Expressed in thyroid, and the digestive tract especially in stomach, cecum and sigmoidal colon (at protein level). Expressed in thyroid.
数据库链接：

KEGG: ssc:397060

STRING: 9823.ENSSSCP00000005038

UniGene: Ssc.33

Recombinant Pig Dual oxidase 2 (DUOX2), partial

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