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  4. Recombinant Pig Dipeptidyl peptidase 4 (DPP4), partial

Recombinant Pig Dipeptidyl peptidase 4 (DPP4), partial

  • 中文名称：
    野猪DPP4重组蛋白
  • 货号：
    CSB-YP007139PI1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    野猪DPP4重组蛋白
  • 货号：
    CSB-EP007139PI1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    野猪DPP4重组蛋白
  • 货号：
    CSB-EP007139PI1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    野猪DPP4重组蛋白
  • 货号：
    CSB-BP007139PI1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    野猪DPP4重组蛋白
  • 货号：
    CSB-MP007139PI1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DPP4
  • Uniprot No.：
    P22411
  • 别名：
    DPP4; CD26; Dipeptidyl peptidase 4; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26; CD antigen CD26
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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DPP4 Proteins

靶点详情

  • 功能：
    Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones such as brain natriuretic peptide 32. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
  • 基因功能参考文献：
    1. This study shows that porcine DPP-IV is generally inhibited with greater potency by protein-derived peptides than is the human enzyme PMID: 25828735
    2. DPP-IV from porcine kidney cortex was characterized. PMID: 21093607
    3. Neutral endopeptidase 24.11 and DPP-IV is superior to DPP-IV inhibition alone in preserving intact GLP-1, which implies possibility that the combination has therapeutic potential. PMID: 16025254
    4. Results describe the distribution of dipeptidyl peptidase IV-like activity enzymes in porcine tissue sections by RT-PCR. PMID: 16700514
  • 亚细胞定位：
    [Dipeptidyl peptidase 4 soluble form]: Secreted.; Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Cell projection, invadopodium membrane; Single-pass type II membrane protein. Cell projection, lamellipodium membrane; Single-pass type II membrane protein. Cell junction. Membrane raft.
  • 蛋白家族：
    Peptidase S9B family, DPPIV subfamily
  • 数据库链接：

    KEGG: ssc:397492

    STRING: 9823.ENSSSCP00000028692

    UniGene: Ssc.16236

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