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  4. Recombinant Mouse Zinc finger CCHC domain-containing protein 12 (Zcchc12)

Recombinant Mouse Zinc finger CCHC domain-containing protein 12 (Zcchc12)

  • 中文名称：
    小鼠Zcchc12重组蛋白
  • 货号：
    CSB-YP866640MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Zcchc12重组蛋白
  • 货号：
    CSB-EP866640MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Zcchc12重组蛋白
  • 货号：
    CSB-EP866640MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Zcchc12重组蛋白
  • 货号：
    CSB-BP866640MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Zcchc12重组蛋白
  • 货号：
    CSB-MP866640MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Zcchc12
  • Uniprot No.：
    Q9CZA5
  • 别名：
    Zcchc12; Sizn1Zinc finger CCHC domain-containing protein 12; Smad-interacting zinc finger protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-402
  • 氨基酸序列
    MASILSRLGS SRGQNSPLPP WAHSMLRSLG RSLGPLMASM AERNMRLFSG RAEPAQGEET FENWLSQVTG VLPDWHMPEE EKVRRLMRTL RGPAREVMRL LQAANPGLDV EDFLRAMKLV FGESESSVTA HSKFVNTVQE HGEKPSLYVI RLEVQLQNAI QAGVFAEREA NQARLHQLLV GAEMSTDLRF RLKNLLRVYA NEPERLPNFL ELIRMIREEE EWEETFINPK RPRRAESVME RALSPMAFQS SPPIMISSID CNVIEIDDSP DDSDEDVILV EPEDPPLPSS SASSFLGRAV SEDQVLVIES PNIFEIQAPS TSSGAGRKNN RGFGELRRAR KRKHTIHCSH CGEEGHSKET CDNESDKGQV FENLIITLQE LTHAEERARG APGEPIGLSE PQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.
  • 基因功能参考文献：
    1. Sizn1 is expressed by Cajal-Retzius neurons of the dorsal forebrain, beginning in their progenitor zones PMID: 21172456
    2. ZCCHC12 enhanced the transcriptional activities of activator protein 1 (AP-1) and cAMP response element binding protein (CREB) as a coactivator PMID: 19578717
  • 蛋白家族：
    ZCCHC12 family
  • 组织特异性：
    In embryonic brains expression is restricted to the ventral region of the forebrain, including the septum, amygdala, caudal putamen, and in the basal-forebrain cholinergic neurons. In adults, expressed in the brain, and at low levels in the testis.
  • 数据库链接：

    KEGG: mmu:72693

    STRING: 10090.ENSMUSP00000044550

    UniGene: Mm.297698

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