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  4. Recombinant Mouse Ubiquinone biosynthesis protein COQ9, mitochondrial (Coq9)

Recombinant Mouse Ubiquinone biosynthesis protein COQ9, mitochondrial (Coq9)

  • 中文名称：
    Recombinant Mouse Ubiquinone biosynthesis protein COQ9, mitochondrial(Coq9)
  • 货号：
    CSB-YP809084MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Ubiquinone biosynthesis protein COQ9, mitochondrial(Coq9)
  • 货号：
    CSB-EP809084MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Ubiquinone biosynthesis protein COQ9, mitochondrial(Coq9)
  • 货号：
    CSB-EP809084MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Ubiquinone biosynthesis protein COQ9, mitochondrial(Coq9)
  • 货号：
    CSB-BP809084MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Ubiquinone biosynthesis protein COQ9, mitochondrial(Coq9)
  • 货号：
    CSB-MP809084MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Coq9
  • Uniprot No.：
    Q8K1Z0
  • 别名：
    Coq9Ubiquinone biosynthesis protein COQ9; mitochondrial
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    46-313
  • 氨基酸序列
    SSEEQ KQQPPHSSSQ QHSETQGPEF SRPPPRYTDQ SGEEEEDYES EEQLQHRILT AALEFVPAHG WTAEAIAEGA QSLGLSSAAA SMFGSDGSEL ILHFVTQCNA RLNQVLEEEQ KLVQLGQAEK RKTDQFLRDA VETRLRMLIP YIEHWPRALS ILLLPHNIPP SLNLLTSMVD DMWHYAGDQS TDFNWYTRRA VLAGIYNTTE LVMMQDSSPD FEDTWRFLEN RINDAMNMGH TAKQVKSTGE ALVQGLMGAA VTLKNLTGLN QRR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Binds a phospholipid of at least 10 carbons in each acyl group. May be required to present its bound-lipid to COQ7.
  • 基因功能参考文献：
    1. The presence of a truncated version of COQ9 protein in Coq9(R239X) mice destabilizes the coenzyme Q10-synthesizing multiprotein complex. PMID: 25802402
    2. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. PMID: 25339443
    3. Lack of a functional Coq9 protein causes predominant encephalomyopathy and CoQ deficiency. PMID: 23255162
    4. Although Pdss2 mutant mice manifest widespread CoQ(9) deficiency and mitochondrial respiratory chain abnormalities, only affected organs show increased ROS production, oxidative stress, mitochondrial DNA depletion, and reduced citrate synthase activity. PMID: 23150520
    5. Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues PMID: 21447381

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  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    COQ9 family
  • 数据库链接：

    KEGG: mmu:67914

    STRING: 10090.ENSMUSP00000034234

    UniGene: Mm.169234

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