Recombinant Mouse Troponin I, slow skeletal muscle (Tnni1)

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中文名称：

小鼠Tnni1重组蛋白
货号：

CSB-EP895293MO
规格：

￥2328
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

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纯度：

Greater than 85% as determined by SDS-PAGE.
基因名：

Tnni1
Uniprot No.：

Q9WUZ5
别名：

Tnni1; Troponin I; slow skeletal muscle; Troponin I; slow-twitch isoform
种属：

Mus musculus (Mouse)
蛋白长度：

Full Length of Mature Protein
来源：

E.coli
分子量：

29.6 kDa
表达区域：

2-187aa
氨基酸序列

PEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLSERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

N-terminal 10xHis-Flag-tagged and C-terminal Myc-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

Tris-based buffer，50% glycerol
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

3-7 business days
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

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功能：

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
基因功能参考文献：
1. data demonstrate that thyroid hormone can alter the time course of ssTnI gene expression in cultured cardiac myocytes and TnI gene regulation is also controlled by some unknown programmed events inside of cardiac myocytes PMID: 15695175
2. a localized N-terminal region of TnI comprised of amino acids 33-80, which interacts with C-terminal regions of cTnC and cTnT, is of particular significance in transducing signaling of thin filament activation by strong cross-bridges PMID: 17099250
3. K+-depolarization increased Tnni1 and Acta1 mRNA levels in both differentiated C2C12 and rat skeletal muscle cells in primary culture PMID: 17146758
4. the up-stream domain ( approximately 1,800 bp) of mouse fetal TnI gene is been cloned and characterized PMID: 18357515
5. Phosphorylation of troponin I was significantly reduced in Galphaq-overexpressing mice compared to wild type. PMID: 18473122
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蛋白家族：

Troponin I family
数据库链接：

KEGG: mmu:21952

STRING: 10090.ENSMUSP00000121343

UniGene: Mm.44379

Recombinant Mouse Troponin I, slow skeletal muscle (Tnni1)

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