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  4. Recombinant Mouse Tetratricopeptide repeat protein 19, mitochondrial (Ttc19)

Recombinant Mouse Tetratricopeptide repeat protein 19, mitochondrial (Ttc19)

  • 中文名称：
    小鼠Ttc19重组蛋白
  • 货号：
    CSB-YP806511MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Ttc19重组蛋白
  • 货号：
    CSB-EP806511MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Ttc19重组蛋白
  • 货号：
    CSB-EP806511MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Ttc19重组蛋白
  • 货号：
    CSB-BP806511MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Ttc19重组蛋白
  • 货号：
    CSB-MP806511MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ttc19
  • Uniprot No.：
    Q8CC21
  • 别名：
    Ttc19; Tetratricopeptide repeat protein 19; mitochondrial; TPR repeat protein 19
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    53-365
  • 氨基酸序列
    HGVLPLLA ALAWFSRPAA TAEQPGEDAS DEAEAEIIQL LKQAKLSIMK DEPEAAELIL HDALRLAYES DNRKAITYTY DLMANLAFIR GQLENAEQLF KATMSYLLGG GMKQEDNAII EISLKLANIY AAQNKQEFAL AGYEFCISTL EGKIEREKEL AEDIMSEETA NTYLLLGMCL DSCARYLLFS KQLSQAQRMY EKALQICQEI QGERHPQTIV LMSDLATTLD AQGHFDDAYI YMQRASDLAR EINHPELHMV LSNLAAILIH RERYTQAKEI YQEALKRAEL KRDEVSVQHI REELAELSRK SRRLT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity.
  • 基因功能参考文献：
    1. UQCRFS1 produces N-terminal polypeptides, which remain bound to holocomplex III. We show that, in normal conditions, these UQCRFS1 fragments are rapidly removed, but when TTC19 is absent they accumulate within complex III, causing its structural and functional impairment. PMID: 28673544
  • 亚细胞定位：
    Mitochondrion inner membrane.
  • 蛋白家族：
    TTC19 family
  • 数据库链接：

    KEGG: mmu:72795

    STRING: 10090.ENSMUSP00000054367

    UniGene: Mm.489722

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