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  4. Recombinant Mouse Testis-expressed sequence 11 protein (Tex11), partial

Recombinant Mouse Testis-expressed sequence 11 protein (Tex11), partial

  • 中文名称：
    小鼠Tex11重组蛋白
  • 货号：
    CSB-YP619906MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Tex11重组蛋白
  • 货号：
    CSB-EP619906MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Tex11重组蛋白
  • 货号：
    CSB-EP619906MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Tex11重组蛋白
  • 货号：
    CSB-BP619906MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Tex11重组蛋白
  • 货号：
    CSB-MP619906MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Tex11
  • Uniprot No.：
    Q14AT2
  • 别名：
    Tex11; Testis-expressed protein 11; Protein ZIP4 homolog; ZIP4H
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.
  • 基因功能参考文献：
    1. Tex11 regulates genome-wide recombination rates in both sexes in a dosage-dependent manner. An intronless autosomal Tex11 transgene functionally substitutes for the X-linked Tex11 gene, providing genetic evidence for the X-to-autosomal retrotransposition evolution phenomenon. PMID: 26136358
    2. mouse spermatogonial stem cells expressed Tex11, Hpip, and Esr2 but not Esr1, and in cultured cells, TEX11 competed with Esr2 for binding to HPIP. PMID: 22383461
    3. TEX11 promotes initiation and/or maintenance of synapsis and formation of crossovers, and may provide a physical link between these two meiotic processes. PMID: 18316482
    4. Zip4h (Tex11), a male germ cell specific X-linked gene was isolated. Zip4h(-/Y) mutant mice were fertile. Analysis of spermatocytes revealed a delay in meiotic double strand break repair and decreased crossover formation. PMID: 18369460
    5. Tex11 was first identified from mouse spermatogonia and was specifically expressed in mouse testis. PMID: 11279525
    6. Tex11 forms discrete foci on meiotic chromosomes. Tex11 is essential for meiosis and fertility in males. Tex11 promotes both chromosomal synapsis and crossover formation in mice and may link these two meiotic processes by interacting with Sycp2 in vivo. PMID: 18316482

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  • 亚细胞定位：
    Chromosome. Note=Forms arrays of discrete foci along synaptonemal complexes in spermatocytes and fetal oocytes.
  • 蛋白家族：
    SPO22 family
  • 组织特异性：
    Testis-specific.
  • 数据库链接：

    KEGG: mmu:83558

    STRING: 10090.ENSMUSP00000009814

    UniGene: Mm.134024

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