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  4. Recombinant Mouse Rho GTPase-activating protein 31 (Arhgap31), partial

Recombinant Mouse Rho GTPase-activating protein 31 (Arhgap31), partial

  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 31(Arhgap31) ,partial
  • 货号：
    CSB-YP408100MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 31(Arhgap31) ,partial
  • 货号：
    CSB-EP408100MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 31(Arhgap31) ,partial
  • 货号：
    CSB-EP408100MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 31(Arhgap31) ,partial
  • 货号：
    CSB-BP408100MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 31(Arhgap31) ,partial
  • 货号：
    CSB-MP408100MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Arhgap31
  • Uniprot No.：
    A6X8Z5
  • 别名：
    Arhgap31; Cdgap; Kiaa1204; Rho GTPase-activating protein 31; Cdc42 GTPase-activating protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration.
  • 基因功能参考文献：
    1. findings are the first to demonstrate the importance of CdGAP in embryonic vascular development and VEGF-induced signaling, and highlight CdGAP as a potential therapeutic target to treat pathological angiogenesis and vascular dysfunction PMID: 27270835
    2. Increased levels of endogenous CdGAP in mammary tumor explant cells resulted in increased cell motility and invasion in response to TGF-beta, and downregulation by siRNA inhibited cell motility and invasion. CdGAP is required for TGF-beta effects. PMID: 21042277
    3. Data show that intersectin-SH3D interacts directly with a small region of CdGAP highly enriched in basic residues and comprising a novel conserved xKx(K/R)K motif. PMID: 21349274
    4. CdGAP is a novel substrate of extracellular signal-regulated kinase (ERK)1/2 and mediates cross talk between the Ras/mitogen-activated protein kinase pathway and regulation of Rac1 activity. PMID: 16024771
  • 亚细胞定位：
    Cell projection, lamellipodium. Cell junction, focal adhesion.
  • 组织特异性：
    Expressed at highest levels in heart and lung.
  • 数据库链接：

    KEGG: mmu:12549

    STRING: 10090.ENSMUSP00000023487

    UniGene: Mm.370848

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