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  4. Recombinant Mouse Protein NEDD1 (Nedd1)

Recombinant Mouse Protein NEDD1 (Nedd1)

  • 中文名称：
    小鼠Nedd1重组蛋白
  • 货号：
    CSB-YP015679MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Nedd1重组蛋白
  • 货号：
    CSB-EP015679MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Nedd1重组蛋白
  • 货号：
    CSB-EP015679MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Nedd1重组蛋白
  • 货号：
    CSB-BP015679MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Nedd1重组蛋白
  • 货号：
    CSB-MP015679MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Nedd1
  • Uniprot No.：
    P33215
  • 别名：
    Nedd1; Nedd-1; Protein NEDD1; Neural precursor cell expressed developmentally down-regulated protein 1; NEDD-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-660
  • 氨基酸序列
    MQENLRFASS GDDVKIWDAS FLTLVDKFNP HTSPHGISSI CWSSNNNFLV TASSSGDKIV VSSCKCKPVP LLELAEGQKQ TCVDLNSTSM YLASGGLNNT VNIWDLKSKR LHRSLKDHKC EVTCVAYNWN DCYIASGSLS GEIILHSVTT NTSSTPFGHG SKQPIRHIKY SLFRKSLLGS VSDNGVVTLW DVNSQSSYHT FDSTHKAPAS GICFSPVNEL LFVTIGLDKR IILYDTSSKK LVKTLVADTP LTAVDFMPDG ATLAIGSSRG KIYQYDLRML KSPVKTISAH KTSVQCIAFQ YSTSLTKASL SKGSSNKATA VNKRSVPVSS SSGAAQNSGI VREAPSPSIA TVLPQPVTTA LGKGSGAAQD EAGLARSKST DIFSKETDAG KSQDFSSFDD TGKNSLGDMF SPIRDDAVVS KGGDESIGKG DGLDFLPQLN SVFPLRKNAG ASSSLVLHSS PLNVLMGSSG KEENESHEPS AESKRAYLGK QEPKDAMKQF TKLISSGAEP GILNTCPSSN QARNLEKFEK PEKDIEAQLI HEPSVNGSST TVPKAASSVT AGVASSLSEK IVDTLGNSRP GAPLTSVQIR FIQNMIQETL DDFREACHRD IVNLQVEMIK QFHIQLNEMH SLLERYSVNE GLVAEIERLR EENKRLRAHF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for mitosis progression. Promotes the nucleation of microtubules from the spindle. May play an important role during the embryonic development and differentiation of the central nervous system.
  • 基因功能参考文献：
    1. The mice treated with small interfering (si) RNA targeting NEDD1 by the atelocollagen-mediated delivery system showed a significantly prolonged survival. PMID: 23106787
    2. Disrupting the centrosome in early-passage mouse embryonic fibroblasts by depletion of NEDD1 also resulted in centrosomal fragmentation and subsequent premature entry into senescence. PMID: 21364642
    3. a direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome PMID: 20224777
    4. NEDD1 is an essential component of acentriolar oocyte MTOCs, which functions in the regulation of meiotic spindle stability PMID: 20079731
    5. the localization of Nedd1 and the centrosome during important processes in mouse embryogenesis and provides a basis for further study into its role in development. PMID: 18239929

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 数据库链接：

    KEGG: mmu:17997

    STRING: 10090.ENSMUSP00000020163

    UniGene: Mm.2998

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