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  4. Recombinant Mouse Protein FAM161A (Fam161a)

Recombinant Mouse Protein FAM161A (Fam161a)

  • 中文名称：
    小鼠Fam161a重组蛋白
  • 货号：
    CSB-YP848082MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Fam161a重组蛋白
  • 货号：
    CSB-EP848082MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Fam161a重组蛋白
  • 货号：
    CSB-EP848082MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Fam161a重组蛋白
  • 货号：
    CSB-BP848082MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Fam161a重组蛋白
  • 货号：
    CSB-MP848082MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Fam161a
  • Uniprot No.：
    Q8QZV6
  • 别名：
    Fam161aProtein FAM161A
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-448
  • 氨基酸序列
    MSKLEKMYQD KLNIKDIQAG FIRDGISDSS SSSASEKSCS HPALSVTSLS EPDLDGSSSL STTTDEGLPD LEEKTPGESS AMVHAQELIN NMWNDFSVED YIQYDSDSRT AKKKRKKAKS LTPKITVPVP FEMTVREQNR REKALSARSD LETKLLKRDE DDAECKKKFR ANPVPSCVLL PLYEDLVKQS EERRKKARER NRAALLASLK PFKFIAREEQ KQAVREKKLR DLFRAKRKTN QFKAKPVPRF IYRPAASDKP KEEELYGDSR MLPKVRDLLQ NSPWPSRSAC RRFRDPRSPA KPRGKHRRRC LRRDGDLEKW KEPFSEYSFL KCPMLCEECC LHESPCDSDK RQKLLADIRA DEEILRETRR PGRSPRRKSP GRSSNPKPRP HECSPPMPTA SSRGREQAIR RSEKARMREY WQELEEQEEK LQKRPMLFER VTQVVFIG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in ciliogenesis.
  • 基因功能参考文献：
    1. Fam161a is required for the molecular delivery into the outer segment cilium, a function which is essential for outer segment disk formation and ultimately visual function. PMID: 24833722
    2. FAM161A-associated RP can be considered as a novel retinal ciliopathy and that its molecular pathogenesis may be related to other ciliopathies. PMID: 22940612
    3. Null mutations in FAM161A are responsible for the RP28-associated autosomal-recessive retinitis pigmentosa. PMID: 20705278
    4. These data suggest a pivotal role for FAM161A in photoreceptors and reveal that FAM161A loss-of-function mutations are a major cause of autosomal-recessive Retinitis pigmentosa. PMID: 20705279
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Note=Localized in the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium.
  • 蛋白家族：
    FAM161 family
  • 组织特异性：
    Expressed in the retina.
  • 数据库链接：

    KEGG: mmu:73873

    UniGene: Mm.252406

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