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  4. Recombinant Mouse PRELI domain-containing protein 1, mitochondrial (Prelid1)

Recombinant Mouse PRELI domain-containing protein 1, mitochondrial (Prelid1)

  • 中文名称：
    小鼠Prelid1重组蛋白
  • 货号：
    CSB-YP854491MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Prelid1重组蛋白
  • 货号：
    CSB-EP854491MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Prelid1重组蛋白
  • 货号：
    CSB-EP854491MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Prelid1重组蛋白
  • 货号：
    CSB-BP854491MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Prelid1重组蛋白
  • 货号：
    CSB-MP854491MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Prelid1
  • Uniprot No.：
    Q8R107
  • 别名：
    Prelid1; Preli; PRELI domain-containing protein 1; mitochondrial; Px19-like protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    36-217
  • 氨基酸序列
    TEDIV HREVTPDQKL LSRRLLTKTN RMPRWAERLF PANVAHSVYI LEDSIVDPQN QTMTTFTWNI NHARLMVVEE RCVYCVNSDN SGWTEIRREA WVSSSLFGVS RAVQEFGLAR FKSNVTKTMK GFEYILAKLQ GEAPSKTLVE TAKEAKEKAK ETALAATEKA KDLANKAATK QQQRQLV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.
  • 基因功能参考文献：
    1. PRELI is a vital LEA B cell protein with failsafe genetics PMID: 22666421
    2. PRELI interacts with OPA1 to maintain mitochondria structures intact, sustain balanced ion(-)/proton(+) gradients, promote oxidative phosphorylation reactions, regulate pro- and antiapoptotic protein traffic and enable cell responses to induced death. PMID: 21364629
    3. Identification of PRELI (protein of relevant evolutionary and lymphoid interest) which encodes a mitochondrial protein and is located on a conserved gene cluster on chromosome 5. PMID: 14640972
  • 亚细胞定位：
    Mitochondrion. Mitochondrion intermembrane space.
  • 组织特异性：
    Abundantly expressed in all tissues tested except testis with highest levels in thymus.
  • 数据库链接：

    KEGG: mmu:66494

    STRING: 10090.ENSMUSP00000021942

    UniGene: Mm.439805

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