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  4. Recombinant Mouse Na (+)/H (+) exchange regulatory cofactor NHE-RF4 (Pdzd3)

Recombinant Mouse Na (+)/H (+) exchange regulatory cofactor NHE-RF4 (Pdzd3)

  • 中文名称：
    小鼠Pdzd3重组蛋白
  • 货号：
    CSB-YP859985MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Pdzd3重组蛋白
  • 货号：
    CSB-EP859985MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Pdzd3重组蛋白
  • 货号：
    CSB-EP859985MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Pdzd3重组蛋白
  • 货号：
    CSB-BP859985MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Pdzd3重组蛋白
  • 货号：
    CSB-MP859985MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Pdzd3
  • Uniprot No.：
    Q99MJ6
  • 别名：
    Pdzd3; Nherf4; Pdzk2Na(+)/H(+) exchange regulatory cofactor NHE-RF4; NHERF-4; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; Na/Pi cotransporter C-terminal-associated protein 2; NaPi-Cap2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Sodium-hydrogen exchanger regulatory factor 4
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-498
  • 氨基酸序列
    MEAAADLRDT ALLTLKFKFN PRLGIDNPVL SLAEDQDQSD PWNLHRPRFC LLSKEEEKTF GFHLQQHLGK ADHVVCRVDP GTSAQRQGLR EGDRILAVNN NIVAHEDHAV VVRYIRASGP RVLLTVLAQH VHDVARVLQG SDAFLCPTLP SGVRPRLCHV VKDEGGFGFS VTHGSRGPFW LVLSAGGAAE RAGVPPGARL LEVNGASVEK LTYNQLNRKL WQSGDQVTLL VAGLEVEEQC HQLGMPLAAP LAEGWALPAK PRCLNIEKGP EGFGFLLREE KGLDGRLGQF LWDVDPGLPA DKAGMKAGDR LVAVAGESVD GLGHEETVSR IRAQGSCVSL IVVDPEADRF FSMVRLSPLL FLENTEIAAP PLAETKDLPV EDTVEPSGLA GSCQCFLYPG PGGGYGFRLC CVASGPCLFI SQVTPGGSTA RAGLQVGDTV LEVNGYPVGG DSELDRLQQL TEAEPPLCLK LGARNPQGLE AWISLESGED WTLASELL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
  • 基因功能参考文献：
    1. Regulation of NHE3 depends on the nature of the NHERF family member associating with NHE3 and the accompanying NHE3 complexes.[IKEPP] PMID: 19088451
    2. PDZK2 is an essential TRPV6 interacting protein as a physiological modulator of TRPV6. PMID: 17645868
  • 亚细胞定位：
    Membrane; Peripheral membrane protein. Cytoplasm.
  • 组织特异性：
    Expressed in kidney and small intestine. Not detected in heart, brain, spleen, lung, liver, skeletal muscle or testis.
  • 数据库链接：

    KEGG: mmu:170761

    UniGene: Mm.29872

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