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Recombinant Mouse Muellerian-inhibiting factor (Amh), partial

In Stock
  • 中文名称:
    Recombinant Mouse Muellerian-inhibiting factor(Amh) ,partial
  • 货号:
    CSB-YP001666MO
  • 规格:
    ¥1836
  • 图片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

产品详情

  • 纯度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 别名:
    Amh; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    Partial
  • 来源:
    Yeast
  • 分子量:
    13.3kDa
  • 表达区域:
    450-552aa
  • 氨基酸序列
    DKGQDGPCALRELSVDLRAERSVLIPETYQANNCQGACRWPQSDRNPRYGNHVVLLLKMQARGAALGRLPCCVPTAYAGKLLISLSEERISADHVPNMVATEC
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签:
    N-terminal 6xHis-tagged
  • 产品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    3-7 business days
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述:

    An NDA sequence corresponding to the 450-552aa of mouse Muellerian-inhibiting factor (Amh) was expressed with an N-terminal 6xHis-tag in the yeast. The resulting protein is the Recombinant partial-length Mouse Mullerian-inhibiting factor (Amh), which has a predicted molecular weight of 13.3 kDa. And it was purified by SDS-PAGE and reached up to 90% in purity. This Amh protein is in-stock, allowing the purchase of no waiting period of product preparation. It may be used as an immunogen for antibody production and in the studies related to sexual differentiation and germ development.

    Amh is a gonadal hormone belonging to the transforming growth factor-beta family. It is restrictedly expressed in Sertoli cells of the fetal and adult testis and granulosa cells of the postnatal ovary. And it plays a significant role in sexual differentiation and germ development. Lack of Amh during female fetal development leads to the development of the Muellerian duct system. And Amh serves as an inhibitor of follicular development and recruitment, which contributes to follicular arrest.
    Elevated expression of Amh is correlated with the various reproductive and metabolic/endocrine alterations in polycystic ovary syndrome (PCOS).

  • Datasheet & COA:
    Please contact us to get it.

产品评价

问答及客户评论

 常见问题解答
Q:

Can you please tell me the concentration for CSB-YP001666MO lot # 03724?

A:
Thanks for your inquiry. The protein concentration of lot # 03724 is 0.1 mg/ml.

靶点详情

  • 功能:
    This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    TGF-beta family
  • 组织特异性:
    Sertoli cells of fetal testes, and testes just after birth, but absent in adult testes. In female, AMH is expressed after birth in the granulosa cells of the follicle. AMH expression is dependent on the degree of follicular maturation and not on the age o
  • 数据库链接: