Recombinant Mouse Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Magi3), partial

中文名称：

小鼠Magi3重组蛋白
货号：

CSB-YP863647MO
规格：
来源：

Yeast
其他：

中文名称：

小鼠Magi3重组蛋白
货号：

CSB-EP863647MO
规格：
来源：

E.coli
其他：

中文名称：

小鼠Magi3重组蛋白
货号：

CSB-EP863647MO-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

小鼠Magi3重组蛋白
货号：

CSB-BP863647MO
规格：
来源：

Baculovirus
其他：

中文名称：

小鼠Magi3重组蛋白
货号：

CSB-MP863647MO
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

Magi3
Uniprot No.：

Q9EQJ9
别名：

Magi3; Kiaa1634Membrane-associated guanylate kinase; WW and PDZ domain-containing protein 3; Membrane-associated guanylate kinase inverted 3; MAGI-3
种属：

Mus musculus (Mouse)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
基因功能参考文献：
1. MAGI-3 has a role in efficient trafficking of TGFalpha to the cell surface in polarized epithelial cells. PMID: 15652357
亚细胞定位：

Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Nucleus.
蛋白家族：

MAGUK family
组织特异性：

Widely expressed. Colocalizes with TGFA in neurons in the cortex and dentate gyrus, as well as in ependymal cells and some astrocytes (at protein level). Present in lens epithelium.
数据库链接：

KEGG: mmu:99470

STRING: 10090.ENSMUSP00000112934

UniGene: Mm.264849

Recombinant Mouse Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Magi3), partial

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