Recombinant Mouse Lymphocyte antigen 6D (Ly6d)

^{In Stock}

中文名称：

Recombinant Mouse Lymphocyte antigen 6D (Ly6d)
货号：

CSB-YP013241MO
规格：

￥2208
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The purity of Ly6d was greater than 90% as determined by SEC-HPLC
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纯度：

Greater than 95% as determined by SDS-PAGE.
Greater than 90% as determined by SEC-HPLC.
生物活性：

Not Test
基因名：

Ly6d
Uniprot No.：

P35459
别名：

Ly-6D;Thymocyte B-cell antigen;ThB
种属：

Mus musculus (Mouse)
蛋白长度：

Full Length of Mature Protein
来源：

Yeast
分子量：

35.6 kDa
表达区域：

21-98aa
氨基酸序列

LRCHVCTNSANCKNPQVCPSNFYFCKTVTSVEPLNGNLVRKECANSCTSDYSQQGHVSSGSEVTQCCQTDLCNERLVS
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

C-terminal mFc-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

3-7 business days
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA：

Please contact us to get it.

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功能：

May act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification.
基因功能参考文献：
1. Expression of RAG-1 and display of Ly6D are both milestone events, but they are neither synchronized nor dependent on each other. PMID: 24023617
2. Data show that ten genes (Fsp27, Aqp4, Cd36, Ly6d, Scd1, Hsd3b5, Syt1, Cyp7b1, and Tff3) showed significant associations among their expressions and the degree of hepatic steatosis. PMID: 19258494
3. identified Ly6d, which divides CLPs into two distinct populations: one that retains full in vivo lymphoid potential and produces more thymocytes at early timepoints than LMPP, and another that behaves essentially as a B-cell progenitor PMID: 19833765
亚细胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
组织特异性：

Lymphoid cells lacking Ly6d, called ALP (all-lymphoid progenitor), retain full lymphoid potential and early thymic seeding activity, whereas cells containing Ly6d, called BLP (B-cell-biased lymphoid progenitor), up-regulate the B-cell specifying factors E
数据库链接：

KEGG: mmu:17068

STRING: 10090.ENSMUSP00000047419

UniGene: Mm.878

Recombinant Mouse Lymphocyte antigen 6D (Ly6d)

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