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  4. Recombinant Mouse Keratin, type I cytoskeletal 15 (Krt15)

Recombinant Mouse Keratin, type I cytoskeletal 15 (Krt15)

  • 中文名称：
    小鼠Krt15重组蛋白
  • 货号：
    CSB-YP717211MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Krt15重组蛋白
  • 货号：
    CSB-EP717211MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Krt15重组蛋白
  • 货号：
    CSB-EP717211MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Krt15重组蛋白
  • 货号：
    CSB-BP717211MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Krt15重组蛋白
  • 货号：
    CSB-MP717211MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Krt15
  • Uniprot No.：
    Q61414
  • 别名：
    Krt15; Krt1-15; Keratin; type I cytoskeletal 15; Cytokeratin-15; CK-15; Keratin-15; K15
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-452
  • 氨基酸序列
    MATTFLQTSS TFGGSSTRGA SLRAGGGSFG GGSLYGGGGS RSISASSARF VSSGAGGGFG GGMSCGFGGG FGGGFGGGFG GGFGDFGGGD GGLLSGNEKV TMQNLNDRLA SYLDKVRALE QANTELEVKI RDWYQKQSPA SPDRDYSHYF KTMEEIRDKI LAATIDNSRV VLEIDNARLA ADDFRLKYEN ELTLRQGVEA DINGLRRVLD ELTLARTDLE MQIEQLNEEL AYLKKNHEEE MKEFSSQLAG QVNVEMDAAP GVDLTRMLAE MREQYEAIAE KNRRDVEAWF FSKTEELNKE VASNTEMIQT SKTEITDLRR TLQGLEIELQ SQLSMKAGLE NSLAEVECRY ATQLQQIQGV ITGLETQLSE LRCEMEAQNQ EYNMLLDIKT RLEQEIATYR NLLEGQDAKM AGIGVREGSS GGGGSSSSSS NFHISVEESV DGKVVSSRKR EI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    In the absence of KRT14, makes a bona fide, but ultrastructurally distinct keratin filament network with KRT5.
  • 基因功能参考文献：
    1. A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse. PMID: 22431489
    2. Krt5 may be a novel biological marker for acute radiation symptoms. PMID: 22692500
    3. K15 protein expression may reflect not only expression in a stem or progenitor cell subpopulation, but also reflects the activity and responsiveness of basal-like cells to loss of homeostasis of the epidermal differentiation program. PMID: 21373883
  • 蛋白家族：
    Intermediate filament family
  • 组织特异性：
    Expressed strongly in the basal cell layer at the tips of rete-like prominences (RLPs) of adult dorsal tongue, outer root sheath (ORS) of hair follicle and skin epidermis (at protein level).
  • 数据库链接：

    KEGG: mmu:16665

    STRING: 10090.ENSMUSP00000103034

    UniGene: Mm.440010

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