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  4. Recombinant Mouse Intraflagellar transport protein 172 homolog (Ift172), partial

Recombinant Mouse Intraflagellar transport protein 172 homolog (Ift172), partial

  • 中文名称：
    小鼠Ift172重组蛋白
  • 货号：
    CSB-YP754431MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Ift172重组蛋白
  • 货号：
    CSB-EP754431MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Ift172重组蛋白
  • 货号：
    CSB-EP754431MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Ift172重组蛋白
  • 货号：
    CSB-BP754431MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Ift172重组蛋白
  • 货号：
    CSB-MP754431MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ift172
  • Uniprot No.：
    Q6VH22
  • 别名：
    Ift172; Kiaa1179; Wim; Intraflagellar transport protein 172 homolog; Protein wimple
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
  • 基因功能参考文献：
    1. Mutation of Ift172 results in a specific class of abnormal cilia and resulting in the VACTERL-like features with hydrocephalus phenotype. PMID: 21653639
    2. Phenotype of the disrupted allele by using CRE expression directed by the prx1 enhancer to disrupt the conditional Ift172 allele in the developing limb. PMID: 19521792
    3. The formation and function of the node and anterior mesendoderm in the mouse embryo relies on an indispensable role of Ift172 in cilia morphogenesis and cilia-mediated signaling. PMID: 18930042
    4. Ift172 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia. PMID: 17971504
  • 亚细胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    IFT172 family
  • 组织特异性：
    Co-localizes with RABL2/RABL2A in the midpiece of elongated spermatids within the testis (at protein level). Expressed in the flagellum of elongated spermatids and sperm in the testis lumen (at protein level).
  • 数据库链接：

    KEGG: mmu:67661

    STRING: 10090.ENSMUSP00000049335

    UniGene: Mm.293023

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