Recombinant Mouse IQ motif and SEC7 domain-containing protein 2 (Iqsec2), partial

中文名称：

小鼠Iqsec2重组蛋白
货号：

CSB-YP691544MO
规格：
来源：

Yeast
其他：

中文名称：

小鼠Iqsec2重组蛋白
货号：

CSB-EP691544MO
规格：
来源：

E.coli
其他：

中文名称：

小鼠Iqsec2重组蛋白
货号：

CSB-EP691544MO-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

小鼠Iqsec2重组蛋白
货号：

CSB-BP691544MO
规格：
来源：

Baculovirus
其他：

中文名称：

小鼠Iqsec2重组蛋白
货号：

CSB-MP691544MO
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

Iqsec2
Uniprot No.：

Q5DU25
别名：

Iqsec2; Kiaa0522IQ motif and SEC7 domain-containing protein 2
种属：

Mus musculus (Mouse)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Is a guanine nucleotide exchange factor for the ARF GTP-binding proteins.
基因功能参考文献：
1. The observations of this study provide support for dosage sensitivity for IQSEC2, which normally escapes X-inactivation in humans and for the first time links these disturbances in expression with specific alterations to the morphology of developing neurons. PMID: 28463240
2. Our present findings suggest that IQ-ArfGEF/BRAG1 may play roles downstream of NMDA receptors through the interaction with multivalent PSD proteins such as IRSp53 and PSD-95.(BRAG1 PROTEIN, MOUSE) PMID: 19083995
3. Iqsec2 (BRAG2)-mediated Arf6 activation triggered by AMPA receptors is the convergent step of different forms of long-term depression and provides an essential mechanism for the control of vesicle formation by endocytic cargo. PMID: 20547133
亚细胞定位：

Cytoplasm.
蛋白家族：

BRAG family
数据库链接：

STRING: 10090.ENSMUSP00000127249

UniGene: Mm.33027

Recombinant Mouse IQ motif and SEC7 domain-containing protein 2 (Iqsec2), partial

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