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  4. Recombinant Mouse Hyccin (Fam126a)

Recombinant Mouse Hyccin (Fam126a)

  • 中文名称：
    小鼠Fam126a重组蛋白
  • 货号：
    CSB-YP754218MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Fam126a重组蛋白
  • 货号：
    CSB-EP754218MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Fam126a重组蛋白
  • 货号：
    CSB-EP754218MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Fam126a重组蛋白
  • 货号：
    CSB-BP754218MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Fam126a重组蛋白
  • 货号：
    CSB-MP754218MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Fam126a
  • Uniprot No.：
    Q6P9N1
  • 别名：
    Fam126a; Drctnnb1a; Hyccin; Down-regulated by CTNNB1 protein A; Protein FAM126A
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-521
  • 氨基酸序列
    MFTSEIGVVE EWLSEFKTLP ETSLPNYATN LKDKSSLVSS LYKVIQEPQS ELLEPVCHQL FEFYRSGEEQ LLRFTLQFLP ELMWCYLAVS ASRDVHSSGC IEALLLGVYN LEIVDKHGHS KVLSFTIPSL SKPSVYHEPS SIGSMALTES ALSQHGLSKV VYSGPHPQRE MLTAQNRFEV LTFLLLCYNA ALTYMPSVSL QSLCQICSRI CVCGYPRQHV RKYRGVSSRI PISSGFMVQM LTGVYFAIYN GEWDLAQKAL DDIIYRAQLE LYPEPLLVAN AIKASLPHGA MKSSKEGTRC IQVEITPTSS RISRNAVTSM SIRGHRWKRH GDTELTGQEE LMDITEVDEG FYSRAASSTS QSGLSNSSHN CSNKTSVGKN QRRSGGSKAG AKERETAGES CRDHFARKQT QRAQSENLEL LSLKRLTLTS SQSLPKPSSQ GLAKTAATVF SKSFEQVSGA PVPRSPSPAI GCVAGADANR FSACSLQEEK LIYVSERTEL AVKCQAGQQG PPSISVTLSA E
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P. Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system. May also have a role in the beta-catenin/Lef signaling pathway.
  • 基因功能参考文献：
    1. Data show that in the brain, Hyccin transcript levels were higher in early postnatal development (postnatal days 2 and 10) and then declined in adult mice. PMID: 22461884
  • 亚细胞定位：
    Cytoplasm, cytosol. Cell membrane.
  • 蛋白家族：
    FAM126 family
  • 组织特异性：
    Predominantly expressed in the central nervous system, where it is found in neurons but not in myelinating cells. Lower abundance is observed in peripheral neurons, where it is detectable only at early postnatal ages. Expressed in both oligodendrocytes an
  • 数据库链接：

    KEGG: mmu:84652

    STRING: 10090.ENSMUSP00000030849

    UniGene: Mm.304976

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