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  4. Recombinant Mouse Homeobox protein BarH-like 2 (Barx2)

Recombinant Mouse Homeobox protein BarH-like 2 (Barx2)

  • 中文名称：
    Recombinant Mouse Homeobox protein BarH-like 2(Barx2)
  • 货号：
    CSB-YP002561MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Homeobox protein BarH-like 2(Barx2)
  • 货号：
    CSB-EP002561MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Homeobox protein BarH-like 2(Barx2)
  • 货号：
    CSB-EP002561MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Homeobox protein BarH-like 2(Barx2)
  • 货号：
    CSB-BP002561MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Homeobox protein BarH-like 2(Barx2)
  • 货号：
    CSB-MP002561MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Barx2
  • Uniprot No.：
    O08686
  • 别名：
    Barx2Homeobox protein BarH-like 2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-283
  • 氨基酸序列
    MHCHAELRLS SPGQLKAARR RYKTFMIDEI LSKETCDYFE KLSLYSVCPS LVVRPKPLHS CTGSPSLRAY PLLSVITRQP TVISHLVPTG SGLTPVLTRH PVAAAEAAAA AAETPGGEAL ASSESETEQP TPRQKKPRRS RTIFTELQLM GLEKKFQKQK YLSTPDRLDL AQSLGLTQLQ VKTWYQNRRM KWKKMVLKGG QEAPTKPKGR PKKNSIPTSE EIEAEEKMNS QAQSQELLES SERQEEPCDT QEPKACLVPL EVAEPIHQPQ ELSEASSEPP PLS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia.
  • 基因功能参考文献：
    1. antagonism between Barx2 and Pax7 in regulation of Wnt signaling may help mediate the switch from myoblast proliferation to differentiation. PMID: 24753152
    2. Barx2 is an important regulator of muscle growth and repair that acts via the control of satellite cell proliferation and differentiation. PMID: 22076929
    3. data suggest a functional network involving Barx2, Fgf10 and matrix metalloproteinases that plays an essential role in regulating branching morphogenesis of the ocular glands. PMID: 21750040
    4. Study show that Barx2 regulates plasticity of immature myofibers and might act as a molecular switch controlling cell differentiation and proliferation. PMID: 20657655
    5. promotes myogenic differentiation and is regulated by myogenic regulatory factors PMID: 12486129
    6. Barx2 homeodomain factor serves as a regulator of hair follicle remodeling (catagen. PMID: 15728386
    7. acts downstream of BMP signaling and in concert with Sox proteins to regulate chondrogenesis PMID: 15800003
    8. BARX2 and estrogen receptor alpha may coordinately regulate cell growth, survival and invasion pathways that are critical to breast cancer progression. PMID: 16636675
    9. Barx2 cooperates with other muscle-expressed transcription factors to regulate the early cytoskeletal remodeling events that underlie efficient myoblast differentiation. PMID: 19269978

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    BAR homeobox family
  • 组织特异性：
    Nervous system, particularly in the telencephalon, spinal cord, and dorsal root ganglia.
  • 数据库链接：

    KEGG: mmu:12023

    STRING: 10090.ENSMUSP00000112314

    UniGene: Mm.261044

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