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  4. Recombinant Mouse GPI-linked NAD (P) (+)--arginine ADP-ribosyltransferase 1 (Art1)

Recombinant Mouse GPI-linked NAD (P) (+)--arginine ADP-ribosyltransferase 1 (Art1)

  • 中文名称：
    Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
  • 货号：
    CSB-YP733724MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
  • 货号：
    CSB-EP733724MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
  • 货号：
    CSB-EP733724MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
  • 货号：
    CSB-BP733724MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
  • 货号：
    CSB-MP733724MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Art1
  • Uniprot No.：
    Q60935
  • 别名：
    Art1; Art2; GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1; EC 2.4.2.31; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1; YAC-1; CD antigen CD296
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    23-290
  • 氨基酸序列
    QSYSISQL DIFSQETPLD MAPASFDDQY AGCLADMTAA LPDLNHSEFQ ANKVYADGWA QANNQWQERR AWGSVWGSLP PSPPGFRDEH GVALLAYTAN SPLHKEFNAA VREAGRSRAH YLHHFSFKTL HFLLTEALQL LRSHRSRGCQ QVYRGVHGLR FRPAGPGATV RLGGFASASL KNVAAQQFGE DTFFGIWTCL GAPIRGYSFF PEEEEVLIPP FETFQVINTS RPTQGPARIY LRALGKRSTY NCEYIKEKKC RSGPCWLGSS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Has ADP-ribosyltransferase activity toward GLP1R.
  • 基因功能参考文献：
    1. The results demonstrated that ART1 gene silencing inhibited the growth of the spleen transplanted tumor and its ability to spread to the liver via metastasis. PMID: 28138708
    2. data suggest that ART1 promoted the expression of HIF-1alpha via the Akt pathway in tumor cells. PMID: 26847718
    3. the apoptosis rate in the ART1-cDNA CT26 cells treated with PARP-1 inhibitor 5-aminoisoquinoline (5-AIQ) and cisplatin increased, when compared with the ART1-cDNA CT26 cells treated with cisplatin only or the untreated ART1-cDNA CT26 cells. PMID: 24676941
    4. ART1 knockdown reduced survival rate correlated with reduced levels of phos-Akt(Thr308) and phos-IkappaBalpha and reduced NF-kappaB p65 nuclear translocation. PMID: 24335275
    5. Successive amino- or carboxyl-terminal truncations of ART1, an arginine-specific transferase, identified regions that regulated transferase and NAD glycohydrolase activities. PMID: 12721285

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  • 亚细胞定位：
    Sarcoplasmic reticulum membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Arg-specific ADP-ribosyltransferase family
  • 组织特异性：
    Abundantly expressed in cardiac and skeletal muscle. Low levels also found in lung.
  • 数据库链接：

    KEGG: mmu:11870

    STRING: 10090.ENSMUSP00000033300

    UniGene: Mm.261071

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