Recombinant Mouse E3 ubiquitin-protein ligase RNF19A (Rnf19a), partial

中文名称：

小鼠Rnf19a重组蛋白
货号：

CSB-YP019866MO
规格：
来源：

Yeast
其他：

中文名称：

小鼠Rnf19a重组蛋白
货号：

CSB-EP019866MO
规格：
来源：

E.coli
其他：

中文名称：

小鼠Rnf19a重组蛋白
货号：

CSB-EP019866MO-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

小鼠Rnf19a重组蛋白
货号：

CSB-BP019866MO
规格：
来源：

Baculovirus
其他：

中文名称：

小鼠Rnf19a重组蛋白
货号：

CSB-MP019866MO
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

Rnf19a
Uniprot No.：

P50636
别名：

Rnf19a; Geg-154; Rnf19; Xybp; E3 ubiquitin-protein ligase RNF19A; EC 2.3.2.31; Double ring-finger protein; Dorfin; Gametogenesis-expressed protein GEG-154; RING finger protein 19A; UBCM4-interacting protein 117; UIP117; XY body protein; XYbp
种属：

Mus musculus (Mouse)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR.
基因功能参考文献：
1. These results suggest that Dorfin may regulate adult neurogenesis, synaptic plasticity, and contextual fear memory. PMID: 26553645
2. In addition to causing a decrease in the amount of mutant SOD1 protein in the spinal cord, Dorfin overexpression ameliorated neurological phenotypes and motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis. PMID: 19610091
亚细胞定位：

Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Expressed primarily in the XY body of pachytene spermatocytes and in the centrosome of somatic and germ cells in all phases of the cell cycle.
蛋白家族：

RBR family, RNF19 subfamily
数据库链接：

KEGG: mmu:30945

STRING: 10090.ENSMUSP00000022890

UniGene: Mm.5181

Recombinant Mouse E3 ubiquitin-protein ligase RNF19A (Rnf19a), partial

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