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  4. Recombinant Mouse Chordin (Chrd), partial

Recombinant Mouse Chordin (Chrd), partial

  • 中文名称：
    Recombinant Mouse Chordin(Chrd) ,partial
  • 货号：
    CSB-YP005377MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Chordin(Chrd) ,partial
  • 货号：
    CSB-EP005377MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Chordin(Chrd) ,partial
  • 货号：
    CSB-EP005377MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Chordin(Chrd) ,partial
  • 货号：
    CSB-BP005377MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Chordin(Chrd) ,partial
  • 货号：
    CSB-MP005377MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Chrd
  • Uniprot No.：
    Q9Z0E2
  • 别名：
    Chrd; Chordin
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
  • 基因功能参考文献：
    1. Chordin upregulated in primary satellite cell cultures and in regenerating muscles PMID: 21645366
    2. The data indicate a role for CV2 and Chd in the establishment of the vertebral morphogenetic field through the long-range relocalization of Chd/BMP complexes. PMID: 20807528
    3. Data show that Brorin-like was predominantly expressed in the adult brain and embryonic neural tissues. PMID: 19852960
    4. role in promoting lineage commitment in embryonic stem cells PMID: 11969257
    5. the BMP antagonists chordin and noggin promote the inductive and trophic activities of rostral organizing centers in early development of the mammalian head PMID: 12397106
    6. chordin antagonism of bone morphogenetic protein signaling and cellular uptake of chordin require cell-surface heparan sulfate proteoglycans PMID: 15381701
    7. results suggest that twisted gastrulation and chordin are involved in osteoblast differentiation and mineralization by regulating BMP signaling PMID: 15780974
    8. These results demonstrate that the chordin contributes to synaptic plasticity and learning likely through a presynaptic mechanism. PMID: 17634368
    9. chordin has a role in venous and arterial patterning and the Bone Morphogenetic Protein pathway is necessary for the process PMID: 17685487
    10. chordin is a modifier for the craniofacial anomalies of Tbx1 mutations. PMID: 19247433

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Chordin family
  • 数据库链接：

    KEGG: mmu:12667

    STRING: 10090.ENSMUSP00000007171

    UniGene: Mm.20457

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