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  4. Recombinant Mouse Centromere protein H (Cenph)

Recombinant Mouse Centromere protein H (Cenph)

  • 中文名称：
    Recombinant Mouse Centromere protein H(Cenph)
  • 货号：
    CSB-YP005211MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Centromere protein H(Cenph)
  • 货号：
    CSB-EP005211MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Centromere protein H(Cenph)
  • 货号：
    CSB-EP005211MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Centromere protein H(Cenph)
  • 货号：
    CSB-BP005211MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Centromere protein H(Cenph)
  • 货号：
    CSB-MP005211MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cenph
  • Uniprot No.：
    Q9QYM8
  • 别名：
    Cenph; Enp; Centromere protein H; CENP-H
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-241
  • 氨基酸序列
    MEEQPRERSE AGAEACEEKR GLSQAAEERI EDRISLLLRL RAQTKQQLLE YKSMIDTNEE KTPEQIMQEK QIEVKIEELE NEIEDVKSNI EMKSLALSRM KLSVALRDNM ENMGPENCVL TDDMKHILKL QKLIMKSQEE SSELEKKLLD VRKKRLQLKQ ASRSKLLEIQ IEKNKQKEDV DKMENSEMIK TMKKKLQTEI KITTVVQHTF QGLILASKTN WAEDPALRET VLQLEKDLNT L
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
  • 基因功能参考文献：
    1. A novel role of CenpH in regulating meiotic G2/M transition by acting via the APC/C(Cdh1)-cyclin B1 pathway. PMID: 27993978
  • 亚细胞定位：
    Nucleus. Chromosome, centromere, kinetochore. Note=Associates with active centromere-kinetochore complexes throughout the cell cycle. Colocalizes with inner kinetochore plate proteins CENPA and CENPC during both interphase and metaphase.
  • 蛋白家族：
    CENP-H/MCM16 family
  • 组织特异性：
    Abundantly expressed in thymus, spleen, uterus, ovary, testis and muscle, and weakly expressed in small intestine, lung and stomach. Barely detectable expression in kidney, liver, skin and prostate gland. Not detected in brain, heart or adrenal gland. Als
  • 数据库链接：

    KEGG: mmu:26886

    STRING: 10090.ENSMUSP00000074988

    UniGene: Mm.273502

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