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Recombinant Mouse CMRF35-like molecule 5 (Cd300ld), partial

  • 中文名称:
    Recombinant Mouse CMRF35-like molecule 5 (Cd300ld), partial
  • 货号:
    CSB-YP840832MO
  • 规格:
    ¥1836
  • 图片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

产品详情

  • 纯度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    Cd300ld
  • Uniprot No.:
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    Partial
  • 来源:
    Yeast
  • 分子量:
    20.0 kDa
  • 表达区域:
    19-177aa
  • 氨基酸序列
    QDSVTGPEEVSGQEQGSLTVQCRYSSYWKGYKKYWCRGVPQRSCDILVETDKSEQLVKKNRVSIRDNQRDFIFTVTMEDLRMSDAGIYWCGITKGGPDPMFKVNVNIDQAPKSSMMTTTATVLKSIQPSAENTGKEQVTQSKEVTQSRPHTRSLLSSIY
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签:
    C-terminal 10xHis-tagged
  • 产品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Acts as an activating receptor in myeloid cells and mast cells.; (Microbial infection) Acts as a functional murine norovirus (MNV) receptor. Primary determinant of MNV species tropism and is sufficient to render cells permissive to infection by MNV. Can render nonmurine mammalian cells susceptible to MNV infection.
  • 基因功能参考文献:
    1. Our results indicate that direct interaction of MNV with two cell-surface molecules, CD300lf and CD300ld, dictates permissive noroviral infection. PMID: 27681626
    2. Data show that LMIR7/CLM-3 shares similarities with LMIR4/CLM-5, although they are differentially regulated in their distribution, expression, and function. PMID: 20817736
    3. the innate immune system is at least in part regulated by the qualitative and quantitative balance of the paired receptors LMIR3 and LMIR4 PMID: 17438331
    4. MAIR-IV may regulate activation of neutrophils and play an important role for innate immunity. PMID: 17543387
  • 亚细胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    CD300 family
  • 组织特异性:
    Expressed in dendritic cells, macrophages and granulocytes. Present on the surface of granulocytes and monocytes/macrophages (at protein level).
  • 数据库链接:

    KEGG: mmu:217305

    UniGene: Mm.275986