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  4. Recombinant Mouse C-Jun-amino-terminal kinase-interacting protein 2 (Mapk8ip2), partial

Recombinant Mouse C-Jun-amino-terminal kinase-interacting protein 2 (Mapk8ip2), partial

  • 中文名称：
    小鼠Mapk8ip2重组蛋白
  • 货号：
    CSB-YP884143MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Mapk8ip2重组蛋白
  • 货号：
    CSB-EP884143MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Mapk8ip2重组蛋白
  • 货号：
    CSB-EP884143MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Mapk8ip2重组蛋白
  • 货号：
    CSB-BP884143MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Mapk8ip2重组蛋白
  • 货号：
    CSB-MP884143MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Mapk8ip2
  • Uniprot No.：
    Q9ERE9
  • 别名：
    Mapk8ip2; Ib2; Jip2; C-Jun-amino-terminal kinase-interacting protein 2; JIP-2; JNK-interacting protein 2; Islet-brain-2; IB-2; JNK MAP kinase scaffold protein 2; Mitogen-activated protein kinase 8-interacting protein 2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells.
  • 基因功能参考文献：
    1. JIP2 does not influence the processing of APP, although it is known that both JIP1b and JIP2 equally regulate the JNK signaling cascade PMID: 12023290
    2. there is a signaling module in which IB2 scaffolds a MLK3/MKK/p38delta kinase cascade. PMID: 12244047
    3. JIP scaffold proteins are critically required for normal NMDA receptor function. PMID: 17875667
    4. Data demonstrate that JIP-2 and -2 proteins can influence insulin-stimulated signal transduction mediated by insulin receptor substrate proteins. PMID: 19564410
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    JIP scaffold family
  • 组织特异性：
    Highly expressed in brain. Expressed in all neurons. Also expressed in testis, primarily in the epididymal epidermis.
  • 数据库链接：

    KEGG: mmu:60597

    STRING: 10090.ENSMUSP00000023291

    UniGene: Mm.173337

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