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  4. Recombinant Mouse BPI fold-containing family B member 1 (Bpifb1)

Recombinant Mouse BPI fold-containing family B member 1 (Bpifb1)

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  • 中文名称：
    Recombinant Mouse BPI fold-containing family B member 1 (Bpifb1)
  • 货号：
    CSB-EP720239MO
  • 规格：
    ￥1536
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性：
    Not Test
  • 基因名：
    Bpifb1
  • Uniprot No.：
    Q61114
  • 别名：
    Long palate, lung and nasal epithelium carcinoma-associated protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    E.coli
  • 分子量：
    57.2 kDa
  • 表达区域：
    22-474aa
  • 氨基酸序列
    NVYPPAVLNLGPEVIQKHLTQALKDHDATAILQELPLLRAMQDKSGSIPILDSFVHTVLRYIIWMKVTSANILQLDVQPSTYDQELVVRIPLDMVAGLNTPLIKTIVEFQMSTEVQALIRVERSKSGPAHLNLSDCSSNESTLRLSLLHKLSFVVNSLAKNVMNLLVPALPQIVKNHLCPVIQQAFDDMYEDFLRLTTAPIALSPGALEFGLLSPAIQDSNILLNLKAKLLDSQARVTNWFNNSATSLMETTPDRAPFSLTVRQDLVNAIVTTLVPKEELVILLRFVIPDVARQLQMDIKEINAEAANKLGPTQMLKIFTHSTPHIVLNEGSARAAQSVVLEVFPTNTDVRPFFSLGIEASYEAQFFTEDNRLMLNFNNVSIERIKLMISDIKLFDPEVLKDTLTKILEYTLLPNENGKLRTGVPMSMSKALGYEKAMWSVSKGALKLTPASS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    C-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • Datasheet & COA：
    Please contact us to get it.

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Bpifb1 Proteins

靶点详情

  • 功能：
    May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS. May be involved in formation of the left-right axis in the node of the developing embryo.
  • 基因功能参考文献：
    1. BPIFB1 is a novel regulator of MUC5B expression in airway mucosa. PMID: 28851744
    2. Bpifb1 mRNA is upregulated in parotid acinar cells in NOD mice, but its expression is not related to the onset of diabetes. These findings suggest that high expression levels of Bpifb1 might predict disease traits before the onset of autoimmunity. PMID: 26769076
    3. Autoimmunity targeting the lung-specific antigen BPIFB1 may contribute to the pathogenesis of interstitial lung disease. PMID: 24107778
    4. Knowledge of the complex expression patterns of BPIF proteins in these regions will allow the use of tractable mouse models of disease to dissect their function. PMID: 22986921
    5. CETP inhibitor torcetrapib promotes reverse cholesterol transport in obese insulin-resistant CETP-ApoB100 transgenic mice PMID: 22212222
    6. a novel gene LPlunc1, a member of BPI/PLUNC gene superfamily, which is asymmetrically expressed in the developing mouse node [LPlunc1 protein] PMID: 14745963

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    BPI/LBP/Plunc superfamily, Plunc family
  • 组织特异性：
    Expressed in tongue, lung, thymus, and stomach. Expressed in epithelia of palate, anterior pharynx, trachea and upper bronchi. Expressed in distal tip of papillae in the anterior third of the tongue and in serous cells of von Ebner glands in the posterior
  • 数据库链接：

    KEGG: mmu:228801

    STRING: 10090.ENSMUSP00000028987

    UniGene: Mm.3783

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