Recombinant Mouse Alpha-defensin 1 (Defa1)

^{In Stock}

中文名称：

Recombinant Mouse Alpha-defensin 1(Defa1)
货号：

CSB-EP006652MO
规格：

￥2328
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

产品详情

纯度：

Greater than 85% as determined by SDS-PAGE.
基因名：

Defa1
Uniprot No.：

P11477
别名：

Defa1; Defcr; Defcr1Alpha-defensin 1; Cryptdin-1; Defensin-related cryptdin peptide
种属：

Mus musculus (Mouse)
蛋白长度：

Full Length of Mature Protein
来源：

E.coli
分子量：

34.1 kDa
表达区域：

59-93aa
氨基酸序列

LRDLVCYCRSRGCKGRERMNGTCRKGHLLYTLCCR
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

N-terminal 6xHis-GST-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

Tris-based buffer,50% glycerol
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

3-7 business days
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

功能：

Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium.
基因功能参考文献：
1. Mouse adenovirus 2 infection was enhanced by enteric alpha-defensins. PMID: 28622386
2. Decreased alpha-defensin is associated with intestinal inflammation in a model of inflammatory bowel disease. PMID: 20222124
3. cryptdin-1 and cryptdin-4 exhibit circadian oscillation PMID: 16129697
4. the Arg5-Glu13 salt bridge in alpha-defensin is conserved for defensin in vivo stability PMID: 16246847
5. MMP-7 activates mouse paneth cell pro-alpha-defensins PMID: 16822871
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亚细胞定位：

Secreted.
蛋白家族：

Alpha-defensin family
组织特异性：

Paneth cells of the small bowel.
数据库链接：

KEGG: mmu:13216

UniGene: Mm.425522