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  4. Recombinant Mouse ATP-binding cassette sub-family B member 7, mitochondrial (Abcb7), partial

Recombinant Mouse ATP-binding cassette sub-family B member 7, mitochondrial (Abcb7), partial

  • 中文名称：
    Recombinant Mouse ATP-binding cassette sub-family B member 7, mitochondrial(Abcb7),partial
  • 货号：
    CSB-YP730723MO1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse ATP-binding cassette sub-family B member 7, mitochondrial(Abcb7),partial
  • 货号：
    CSB-EP730723MO1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse ATP-binding cassette sub-family B member 7, mitochondrial(Abcb7),partial
  • 货号：
    CSB-EP730723MO1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse ATP-binding cassette sub-family B member 7, mitochondrial(Abcb7),partial
  • 货号：
    CSB-BP730723MO1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse ATP-binding cassette sub-family B member 7, mitochondrial(Abcb7),partial
  • 货号：
    CSB-MP730723MO1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Abcb7
  • Uniprot No.：
    Q61102
  • 别名：
    Abcb7; Abc7; Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ABC transporter 7 protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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Abcb7 Proteins

靶点详情

  • 功能：
    Exports glutathione-coordinated iron-sulfur clusters such as [2Fe-2S]-(GS)4 cluster from the mitochondria to the cytosol in an ATP-dependent manner allowing the assembly of the cytosolic iron-sulfur (Fe/S) cluster-containing proteins and participates in iron homeostasis. Moreover, through a functional complex formed of ABCB7, FECH and ABCB10, also plays a role in the cellular iron homeostasis, mitochondrial function and heme biosynthesis. In cardiomyocytes, regulates cellular iron homeostasis and cellular reactive oxygen species (ROS) levels through its interaction with COX4I1. May also play a role in hematopoiesis.
  • 基因功能参考文献：
    1. ABC7 positively regulates the expression of extramitochondrial thioredoxin & that of an intramitochondrial iron-sulfur-containing protein, ferrochelatase. ABC7 contributes to the production of heme during the differentiation of erythroid cells. PMID: 12480705
    2. Abcb7 is an essential gene associated with X-linked parent of origin lethality in mice and required for development or maintenance of adult cell lineages. PMID: 16467350
  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ABC transporter superfamily, ABCB family, Heavy Metal importer (TC 3.A.1.210) subfamily
  • 数据库链接：

    KEGG: mmu:11306

    STRING: 10090.ENSMUSP00000033695

    UniGene: Mm.426128

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