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  4. Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 7 (Adamts7), partial

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 7 (Adamts7), partial

  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 货号：
    CSB-YP737909MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 货号：
    CSB-EP737909MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 货号：
    CSB-EP737909MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 货号：
    CSB-BP737909MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 货号：
    CSB-MP737909MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Adamts7
  • Uniprot No.：
    Q68SA9
  • 别名：
    Adamts7A disintegrin and metalloproteinase with thrombospondin motifs 7; ADAM-TS 7; ADAM-TS7; ADAMTS-7; EC 3.4.24.-; COMPase
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Metalloprotease that may play a role in the degradation of COMP.
  • 基因功能参考文献：
    1. Therefore, these data provided the in vivo evidence, suggesting that ADAMTS-7 may play an important role in the pathogenesis of inflammatory arthritis. PMID: 25742929
    2. Mice lacking Adamts7, Ldlr, Apoe had less lesion formation in aortas and aortic roots vs controls and less neointimal formation after femoral wire injury. Adamts7 expression was induced by injury and hyperlipidemia. PMID: 25712206
    3. Adamts-7 deficiency substantially ameliorated neointima formation in mice at days 14 and 28 after injury. ADAMTS-7 inhibited both endothelial cell proliferation and migration. PMID: 25712208
    4. The overexpression of ADATMTS-7 might contribute to early inflammatory kidney damage associated with aging PMID: 24642842
    5. ADAMTS-7 and TNF-alpha form a positive feedback loop in the regulation of cartilage degradation and osteoarthritis progression. PMID: 23928557
    6. ADAMTS7B has a domain organization with a total of eight thrombospondin type 1 repeats in its ancillary domain. Of these, seven are arranged in two distinct clusters that are separated by a mucin domain PMID: 15192113
    7. Findings demonstrate that ADAMTS-7, a direct target of PTHrP signaling, negatively regulates endochondral bone formation by associating with and inactivating GEP chondrogenic growth factor. PMID: 19487464

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix. Note=Also found associated with the external cell surface.
  • 数据库链接：

    KEGG: mmu:108153

    STRING: 10090.ENSMUSP00000108683

    UniGene: Mm.102141

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