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  4. Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 2 (Adamts2), partial

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 2 (Adamts2), partial

  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 2(Adamts2) ,partial
  • 货号：
    CSB-YP804012MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 2(Adamts2) ,partial
  • 货号：
    CSB-EP804012MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 2(Adamts2) ,partial
  • 货号：
    CSB-EP804012MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 2(Adamts2) ,partial
  • 货号：
    CSB-BP804012MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 2(Adamts2) ,partial
  • 货号：
    CSB-MP804012MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Adamts2
  • Uniprot No.：
    Q8C9W3
  • 别名：
    Adamts2A disintegrin and metalloproteinase with thrombospondin motifs 2; ADAM-TS 2; ADAM-TS2; ADAMTS-2; EC 3.4.24.14; Procollagen I N-proteinase; PC I-NP; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase; pNPI
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form with reduced collagen-binding activity.
  • 基因功能参考文献：
    1. ADAMTS2 plays a critical role in cardiac hypertrophy induced by pressure overload in mouse model. PMID: 28373586
    2. Data show that the high titer and specific rabbit anti-ADAMTS2 antibody has been prepared successfully. PMID: 26927563
    3. There is no significant genotype effect of ADAMTS2 on age, height, weight, BMI or sex on risk of Achilles tendon pathology. PMID: 23491141
    4. Data show that ADAMTS-2 is able to reduce proliferation of endothelial cells, and to induce their retraction and detachment from the substrate resulting in apoptosis. PMID: 20574651
    5. The extent of liver fibrosis is reduced in ADAMTS2-deficient mice in comparison with their wild type littermates. PMID: 17929299
    6. Data show thatincreased mRNA of Lamb3 and Adamts2 and enhanced activities of metalloproteinases MMP1, 2 and 7 in transgenic mice expressing the HLA-DQ8. PMID: 19795413

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 数据库链接：

    KEGG: mmu:216725

    STRING: 10090.ENSMUSP00000040171

    UniGene: Mm.110597

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