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  4. Recombinant Human snRNA-activating protein complex subunit 2 (SNAPC2)

Recombinant Human snRNA-activating protein complex subunit 2 (SNAPC2)

  • 中文名称：
    人SNAPC2重组蛋白
  • 货号：
    CSB-YP621673HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SNAPC2重组蛋白
  • 货号：
    CSB-EP621673HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SNAPC2重组蛋白
  • 货号：
    CSB-EP621673HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SNAPC2重组蛋白
  • 货号：
    CSB-BP621673HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SNAPC2重组蛋白
  • 货号：
    CSB-MP621673HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SNAPC2
  • Uniprot No.：
    Q13487
  • 别名：
    SNAPC2; SNAP45; snRNA-activating protein complex subunit 2; SNAPc subunit 2; Proximal sequence element-binding transcription factor subunit delta; PSE-binding factor subunit delta; PTF subunit delta; Small nuclear RNA-activating complex polypeptide 2; snRNA-activating protein complex 45 kDa subunit; SNAPc 45 kDa subunit
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-334
  • 氨基酸序列
    MKPPPRRRAA PARYLGEVTG PATWSAREKR QLVRLLQARQ GQPEPDATEL ARELRGRSEA EIRVFLQQLK GRVAREAIQK VHPGGLQGPR RREAQPPAPI EVWTDLAEKI TGPLEEALAV AFSQVLTIAA TEPVTLLHSK PPKPTQARGK PLLLSAPGGQ EDPAPEIPSS APAAPSSAPR TPDPAPEKPS ESSAGPSTEE DFAVDFEKIY KYLSSVSRSG RSPELSAAES AVVLDLLMSL PEELPLLPCT ALVEHMTETY LRLTAPQPIP AGGSLGPAAE GDGAGSKAPE ETPPATEKAE HSELKSPWQA AGICPLNPFL VPLELLGRAA TPAR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
  • 基因功能参考文献：
    1. The findings invoke a model wherein incomplete DNA synthesis during S phase leads to a DNA damage response and formation of 53BP1-OPT domains in the subsequent G1. PMID: 21444690
    2. SNAP45 plays two roles in the cell, one as a subunit of the transcription factor SNAP(c) and another as a factor required for proper mitotic progression PMID: 18356157
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 11135

    OMIM: 605076

    KEGG: hsa:6618

    STRING: 9606.ENSP00000221573

    UniGene: Hs.631860

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