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  4. Recombinant Human p53 and DNA damage-regulated protein 1 (PDRG1)

Recombinant Human p53 and DNA damage-regulated protein 1 (PDRG1)

  • 中文名称：
    人PDRG1重组蛋白
  • 货号：
    CSB-EP878890HU
  • 规格：
    ￥1344
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    PDRG1
  • Uniprot No.：
    Q9NUG6
  • 别名：
    PDRG1; C20orf126; PDRGp53 and DNA damage-regulated protein 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length
  • 来源：
    E.coli
  • 分子量：
    31.5kDa
  • 表达区域：
    1-133aa
  • 氨基酸序列
    MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMPHPETKEMIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLNQDELKALKVILKG
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-SUMO-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

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PDRG1 antibodies

PDRG1 Proteins

靶点详情

  • 功能：
    May play a role in chaperone-mediated protein folding.
  • 基因功能参考文献：
    1. It was found that PDRG1 could promote radio-resistance that involved the ATM-p53 signaling pathway in lung cancer cells. PMID: 27610824
    2. PDRG1 was significantly increased in tumors low of miR-214. PMID: 25706919
    3. PDRG1 expression is increased in multiple human malignancies suggesting it to be a high-value novel tumor marker that could play a role in cancer development and/or progression. PMID: 21193842
    4. Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation PMID: 14562055
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Prefoldin subunit beta family
  • 组织特异性：
    Predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs.
  • 数据库链接：

    HGNC: 16119

    OMIM: 610789

    KEGG: hsa:81572

    STRING: 9606.ENSP00000202017

    UniGene: Hs.435755

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