Recombinant Human WD repeat- and FYVE domain-containing protein 4 (WDFY4), partial

中文名称：

人WDFY4重组蛋白
货号：

CSB-YP747798HU
规格：
来源：

Yeast
其他：

中文名称：

人WDFY4重组蛋白
货号：

CSB-EP747798HU
规格：
来源：

E.coli
其他：

中文名称：

人WDFY4重组蛋白
货号：

CSB-EP747798HU-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

人WDFY4重组蛋白
货号：

CSB-BP747798HU
规格：
来源：

Baculovirus
其他：

中文名称：

人WDFY4重组蛋白
货号：

CSB-MP747798HU
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

WDFY4
Uniprot No.：

Q6ZS81
别名：

WDFY4; C10orf64; KIAA1607WD repeat- and FYVE domain-containing protein 4
种属：

Homo sapiens (Human)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
基因功能参考文献：
1. A significantly increased risk for RA associated with the WDFY4 rs7097397 AG genotype. PMID: 24549174
2. rs877819 SNP in WDFY4 may be associated with systemic lupus erythematosus by reduced binding of YY1 and downregulating WDFY4 expression. PMID: 22972472
3. Genetic variants in ETS1 and WDFY4 were found to be associated with systemic lupus erythematosus, in the Asian population studied. PMID: 20169177
亚细胞定位：

Early endosome. Endoplasmic reticulum.
数据库链接：

HGNC: 29323

OMIM: 613316

KEGG: hsa:57705

STRING: 9606.ENSP00000320563

UniGene: Hs.287379

Recombinant Human WD repeat- and FYVE domain-containing protein 4 (WDFY4), partial

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