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  4. Recombinant Human UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (B3GALNT1), partial

Recombinant Human UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (B3GALNT1), partial

  • 中文名称：
    Recombinant Human UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1(B3GALNT1), partial
  • 货号：
    CSB-YP002488HU1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1(B3GALNT1), partial
  • 货号：
    CSB-EP002488HU1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1(B3GALNT1), partial
  • 货号：
    CSB-EP002488HU1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1(B3GALNT1), partial
  • 货号：
    CSB-BP002488HU1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1(B3GALNT1), partial
  • 货号：
    CSB-MP002488HU1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    B3GALNT1
  • Uniprot No.：
    O75752
  • 别名：
    B3GALNT1; B3GALT3; UNQ531/PRO1074; UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; Beta-1,3-GalNAc-T1; Beta-1,3-galactosyltransferase 3; Beta-1,3-GalTase 3; Beta3Gal-T3; Beta3GalT3; b3Gal-T3; Beta-3-Gx-T3; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; Globoside synthase; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    partial, Lumenal domain
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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B3GALNT1 Proteins

靶点详情

  • 功能：
    Transfers N-acetylgalactosamine onto globotriaosylceramide. Plays a critical role in preimplantation stage embryonic development.
  • 基因功能参考文献：
    1. b1,3GalNAc-T1 uses different acceptors to form immunologically distinct glycosphingolipids. PMID: 26055721
    2. TINAGL1 and B3GALNT1 are possible candidates for drug compounds that inhibit their gene expression PMID: 25521548
    3. The Pk phenotype is resulted from 433 C>T mutation in the B3GALNT1 gene. PMID: 26037356
    4. The N-acetylgalactose aminotransferase gene 539G>C mutation resulted in A2B phenotype generation, and individual serum contained the anti-A1 antibody. PMID: 24782133
    5. The number of GLOB-null alleles was increased by 50%. PMID: 23927681
    6. identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase gene involved in globoside-deficient P(k) blood group phenotype PMID: 12023287
    7. Eighteen SNPs in the MC1R gene and P genes were genotyped in 52 individuals by the direct sequencing method, and 4 SNPs (MC1R gene: R163Q and P gene: IVS5 + 1001, IVS13 + 113, and H615R) were selected on the basis of differences in frequencies. PMID: 18839200

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  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 组织特异性：
    Higher expression in heart and brain, and to a lesser extent in lung, placenta, kidney and testis. Lower expression in liver, spleen and stomach. No expression in skeletal muscle.
  • 数据库链接：

    HGNC: 918

    OMIM: 111400

    KEGG: hsa:8706

    STRING: 9606.ENSP00000323479

    UniGene: Hs.418062

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